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Prolonged cenicriviroc therapy reduces hepatic fibrosis despite steatohepatitis in a diet-induced mouse model of nonalcoholic steatohepatitis.
Kruger AJ, Fuchs BC, Masia R, Holmes JA, Salloum S, Sojoodi M, Ferreira DS, Rutledge SM, Caravan P, Alatrakchi N, Vig P, Lefebvre E, Chung RT. Kruger AJ, et al. Among authors: holmes ja. Hepatol Commun. 2018 Mar 7;2(5):529-545. doi: 10.1002/hep4.1160. eCollection 2018 May. Hepatol Commun. 2018. PMID: 29761169 Free PMC article.
Exposure to human immunodeficiency virus/hepatitis C virus in hepatic and stellate cell lines reveals cooperative profibrotic transcriptional activation between viruses and cell types.
Salloum S, Holmes JA, Jindal R, Bale SS, Brisac C, Alatrakchi N, Lidofsky A, Kruger AJ, Fusco DN, Luther J, Schaefer EA, Lin W, Yarmush ML, Chung RT. Salloum S, et al. Among authors: holmes ja. Hepatology. 2016 Dec;64(6):1951-1968. doi: 10.1002/hep.28766. Epub 2016 Oct 5. Hepatology. 2016. PMID: 27531241 Free PMC article.
Lupus-like Immune Complex-mediated Glomerulonephritis in Patients with Hepatitis C Virus Infection Treated with Oral, Interferon-free, Direct-acting Antiviral Therapy.
Sise ME, Wisocky J, Rosales IA, Chute D, Holmes JA, Corapi KM, Babitt JL, Tangren JS, Hashemi N, Lundquist AL, Williams WW, Mount DB, Andersson KL, Rennke HG, Smith RN, Colvin R, Thadhani RI, Chung RT. Sise ME, et al. Among authors: holmes ja. Kidney Int Rep. 2016 Sep;1(3):135-143. doi: 10.1016/j.ekir.2016.06.006. Kidney Int Rep. 2016. PMID: 27990496 Free PMC article.
Tyrosine kinase SYK is a potential therapeutic target for liver fibrosis.
Qu C, Zheng D, Li S, Liu Y, Lidofsky A, Holmes JA, Chen J, He L, Wei L, Liao Y, Yuan H, Jin Q, Lin Z, Hu Q, Jiang Y, Tu M, Chen X, Li W, Lin W, Fuchs BC, Chung RT, Hong J. Qu C, et al. Among authors: holmes ja. Hepatology. 2018 Sep;68(3):1125-1139. doi: 10.1002/hep.29881. Epub 2018 May 21. Hepatology. 2018. PMID: 29537660 Free PMC article.
Macrophage Activation Marker Soluble CD163 Is a Dynamic Marker of Liver Fibrogenesis in Human Immunodeficiency Virus/Hepatitis C Virus Coinfection.
Lidofsky A, Holmes JA, Feeney ER, Kruger AJ, Salloum S, Zheng H, Seguin IS, Altinbas A, Masia R, Corey KE, Gustafson JL, Schaefer EA, Hunt PW, Deeks S, Somsouk M, Chew KW, Chung RT, Alatrakchi N. Lidofsky A, et al. Among authors: holmes ja. J Infect Dis. 2018 Sep 22;218(9):1394-1403. doi: 10.1093/infdis/jiy331. J Infect Dis. 2018. PMID: 29868909 Free PMC article.
188 results