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Page 1
Advances in drug discovery for human beta cell regeneration.
Karakose E, Ackeifi C, Wang P, Stewart AF. Karakose E, et al. Among authors: ackeifi c. Diabetologia. 2018 Aug;61(8):1693-1699. doi: 10.1007/s00125-018-4639-6. Epub 2018 May 16. Diabetologia. 2018. PMID: 29770834 Free PMC article. Review.
Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells.
Wang P, Karakose E, Liu H, Swartz E, Ackeifi C, Zlatanic V, Wilson J, González BJ, Bender A, Takane KK, Ye L, Harb G, Pagliuca F, Homann D, Egli D, Argmann C, Scott DK, Garcia-Ocaña A, Stewart AF. Wang P, et al. Among authors: ackeifi c. Cell Metab. 2019 Mar 5;29(3):638-652.e5. doi: 10.1016/j.cmet.2018.12.005. Epub 2018 Dec 20. Cell Metab. 2019. PMID: 30581122 Free PMC article.
GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration.
Ackeifi C, Wang P, Karakose E, Manning Fox JE, González BJ, Liu H, Wilson J, Swartz E, Berrouet C, Li Y, Kumar K, MacDonald PE, Sanchez R, Thorens B, DeVita R, Homann D, Egli D, Scott DK, Garcia-Ocaña A, Stewart AF. Ackeifi C, et al. Sci Transl Med. 2020 Feb 12;12(530):eaaw9996. doi: 10.1126/scitranslmed.aaw9996. Sci Transl Med. 2020. PMID: 32051230 Free PMC article.
A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS.
Yang YM, Gupta SK, Kim KJ, Powers BE, Cerqueira A, Wainger BJ, Ngo HD, Rosowski KA, Schein PA, Ackeifi CA, Arvanites AC, Davidow LS, Woolf CJ, Rubin LL. Yang YM, et al. Among authors: ackeifi ca. Cell Stem Cell. 2013 Jun 6;12(6):713-26. doi: 10.1016/j.stem.2013.04.003. Epub 2013 Apr 18. Cell Stem Cell. 2013. PMID: 23602540 Free PMC article.
TNF-α inhibitors for type 1 diabetes: exploring the path to a pivotal clinical trial.
Bazile C, Abdel Malik MM, Ackeifi C, Anderson RL, Beck RW, Donath MY, Dutta S, Hedrick JA, Karpen SR, Kay TWH, Marder T, Marinac M, McVean J, Meyer R, Pettus J, Quattrin T, Verstegen RHJ, Vieth JA, Latres E. Bazile C, et al. Among authors: ackeifi c. Front Immunol. 2024 Oct 1;15:1470677. doi: 10.3389/fimmu.2024.1470677. eCollection 2024. Front Immunol. 2024. PMID: 39411715 Free PMC article. Review.