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902 results

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Page 1
Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial.
Sprigg N, Flaherty K, Appleton JP, Al-Shahi Salman R, Bereczki D, Beridze M, Christensen H, Ciccone A, Collins R, Czlonkowska A, Dineen RA, Duley L, Egea-Guerrero JJ, England TJ, Krishnan K, Laska AC, Law ZK, Ozturk S, Pocock SJ, Roberts I, Robinson TG, Roffe C, Seiffge D, Scutt P, Thanabalan J, Werring D, Whynes D, Bath PM; TICH-2 Investigators. Sprigg N, et al. Among authors: flaherty k. Lancet. 2018 May 26;391(10135):2107-2115. doi: 10.1016/S0140-6736(18)31033-X. Epub 2018 May 16. Lancet. 2018. PMID: 29778325 Free PMC article. Clinical Trial.
Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT.
Sprigg N, Flaherty K, Appleton JP, Al-Shahi Salman R, Bereczki D, Beridze M, Ciccone A, Collins R, Dineen RA, Duley L, Egea-Guerrero JJ, England TJ, Karlinski M, Krishnan K, Laska AC, Law ZK, Ovesen C, Ozturk S, Pocock SJ, Roberts I, Robinson TG, Roffe C, Peters N, Scutt P, Thanabalan J, Werring D, Whynes D, Woodhouse L, Bath PM. Sprigg N, et al. Among authors: flaherty k. Health Technol Assess. 2019 Jul;23(35):1-48. doi: 10.3310/hta23350. Health Technol Assess. 2019. PMID: 31322116 Free PMC article. Clinical Trial.
Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial.
Bath PM, Woodhouse LJ, Appleton JP, Beridze M, Christensen H, Dineen RA, Duley L, England TJ, Flaherty K, Havard D, Heptinstall S, James M, Krishnan K, Markus HS, Montgomery AA, Pocock SJ, Randall M, Ranta A, Robinson TG, Scutt P, Venables GS, Sprigg N; TARDIS Investigators. Bath PM, et al. Among authors: flaherty k. Lancet. 2018 Mar 3;391(10123):850-859. doi: 10.1016/S0140-6736(17)32849-0. Epub 2017 Dec 20. Lancet. 2018. PMID: 29274727 Free PMC article. Clinical Trial.
Does tranexamic acid lead to changes in MRI measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? Protocol for a MRI substudy nested within the double-blind randomised controlled TICH-2 trial.
Dineen RA, Pszczolkowski S, Flaherty K, Law ZK, Morgan PS, Roberts I, Werring DJ, Al-Shahi Salman R, England T, Bath PM, Sprigg N. Dineen RA, et al. Among authors: flaherty k. BMJ Open. 2018 Feb 3;8(2):e019930. doi: 10.1136/bmjopen-2017-019930. BMJ Open. 2018. PMID: 29431141 Free PMC article. Clinical Trial.
Prevention of haematoma progression by tranexamic acid in intracerebral haemorrhage patients with and without spot sign on admission scan: a statistical analysis plan of a pre-specified sub-study of the TICH-2 trial.
Ovesen C, Jakobsen JC, Gluud C, Steiner T, Law Z, Flaherty K, Dineen RA, Bath PM, Sprigg N, Christensen H. Ovesen C, et al. Among authors: flaherty k. BMC Res Notes. 2018 Jun 13;11(1):379. doi: 10.1186/s13104-018-3481-8. BMC Res Notes. 2018. PMID: 29895329 Free PMC article. Clinical Trial.
Baseline characteristics of the 3096 patients recruited into the 'Triple Antiplatelets for Reducing Dependency after Ischemic Stroke' trial.
Bath PM, Appleton JP, Beridze M, Christensen H, Dineen RA, Duley L, England TJ, Heptinstall S, James M, Krishnan K, Markus HS, Pocock S, Ranta A, Robinson TG, Flaherty K, Scutt P, Venables GS, Woodhouse LJ, Sprigg N. Bath PM, et al. Among authors: flaherty k. Int J Stroke. 2017 Jul;12(5):524-538. doi: 10.1177/1747493016677988. Epub 2016 Nov 4. Int J Stroke. 2017. PMID: 27811309 Free article. Clinical Trial.
Preventing cognitive decline and dementia from cerebral small vessel disease: The LACI-1 Trial. Protocol and statistical analysis plan of a phase IIa dose escalation trial testing tolerability, safety and effect on intermediary endpoints of isosorbide mononitrate and cilostazol, separately and in combination.
Blair GW, Appleton JP, Law ZK, Doubal F, Flaherty K, Dooley R, Shuler K, Richardson C, Hamilton I, Shi Y, Stringer M, Boyd J, Thrippleton MJ, Sprigg N, Bath PM, Wardlaw JM. Blair GW, et al. Among authors: flaherty k. Int J Stroke. 2018 Jul;13(5):530-538. doi: 10.1177/1747493017731947. Epub 2017 Sep 14. Int J Stroke. 2018. PMID: 28906205 Clinical Trial.
902 results