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Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety.
Dedic N, Kühne C, Jakovcevski M, Hartmann J, Genewsky AJ, Gomes KS, Anderzhanova E, Pöhlmann ML, Chang S, Kolarz A, Vogl AM, Dine J, Metzger MW, Schmid B, Almada RC, Ressler KJ, Wotjak CT, Grinevich V, Chen A, Schmidt MV, Wurst W, Refojo D, Deussing JM. Dedic N, et al. Among authors: deussing jm. Nat Neurosci. 2018 Jun;21(6):803-807. doi: 10.1038/s41593-018-0151-z. Epub 2018 May 21. Nat Neurosci. 2018. PMID: 29786085 Free PMC article.
Corticotropin-releasing hormone activates ERK1/2 MAPK in specific brain areas.
Refojo D, Echenique C, Müller MB, Reul JM, Deussing JM, Wurst W, Sillaber I, Paez-Pereda M, Holsboer F, Arzt E. Refojo D, et al. Among authors: deussing jm. Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6183-8. doi: 10.1073/pnas.0502070102. Epub 2005 Apr 15. Proc Natl Acad Sci U S A. 2005. PMID: 15833812 Free PMC article.
168 results