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Mutational analysis confirms the presence of distal inhibitor-selectivity determining residues in B. stearothermophilus dihydrofolate reductase.
Eck T, Patel S, Candela T, Leon H K, Little M, Reis NE, Liyanagunawardana U, Gubler U, Janson CA, Catalano J, Goodey NM. Eck T, et al. Among authors: goodey nm. Arch Biochem Biophys. 2020 Oct 15;692:108545. doi: 10.1016/j.abb.2020.108545. Epub 2020 Aug 15. Arch Biochem Biophys. 2020. PMID: 32810476 Free PMC article.
Investigating the Roles of Active Site Residues in Mycobacterium tuberculosis Indole-3-glycerol Phosphate Synthase, a Potential Target for Antitubercular Agents.
Konas DW, Cho S, Thomas OD, Bhatti MM, Leon Hernandez K, Moran C, Booter H, Candela T, Lacap J, McFadden P, van den Berg S, Welter AM, Peralta A, Janson CA, Catalano J, Goodey NM. Konas DW, et al. Among authors: goodey nm. ACS Bio Med Chem Au. 2023 Jul 26;3(5):438-447. doi: 10.1021/acsbiomedchemau.3c00029. eCollection 2023 Oct 18. ACS Bio Med Chem Au. 2023. PMID: 37876495 Free PMC article.
28 results