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Page 1
Precise control of SCRaMbLE in synthetic haploid and diploid yeast.
Jia B, Wu Y, Li BZ, Mitchell LA, Liu H, Pan S, Wang J, Zhang HR, Jia N, Li B, Shen M, Xie ZX, Liu D, Cao YX, Li X, Zhou X, Qi H, Boeke JD, Yuan YJ. Jia B, et al. Among authors: mitchell la. Nat Commun. 2018 May 22;9(1):1933. doi: 10.1038/s41467-018-03084-4. Nat Commun. 2018. PMID: 29789567 Free PMC article.
SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes.
Shen Y, Stracquadanio G, Wang Y, Yang K, Mitchell LA, Xue Y, Cai Y, Chen T, Dymond JS, Kang K, Gong J, Zeng X, Zhang Y, Li Y, Feng Q, Xu X, Wang J, Wang J, Yang H, Boeke JD, Bader JS. Shen Y, et al. Among authors: mitchell la. Genome Res. 2016 Jan;26(1):36-49. doi: 10.1101/gr.193433.115. Epub 2015 Nov 13. Genome Res. 2016. PMID: 26566658 Free PMC article.
Engineering the ribosomal DNA in a megabase synthetic chromosome.
Zhang W, Zhao G, Luo Z, Lin Y, Wang L, Guo Y, Wang A, Jiang S, Jiang Q, Gong J, Wang Y, Hou S, Huang J, Li T, Qin Y, Dong J, Qin Q, Zhang J, Zou X, He X, Zhao L, Xiao Y, Xu M, Cheng E, Huang N, Zhou T, Shen Y, Walker R, Luo Y, Kuang Z, Mitchell LA, Yang K, Richardson SM, Wu Y, Li BZ, Yuan YJ, Yang H, Lin J, Chen GQ, Wu Q, Bader JS, Cai Y, Boeke JD, Dai J. Zhang W, et al. Among authors: mitchell la. Science. 2017 Mar 10;355(6329):eaaf3981. doi: 10.1126/science.aaf3981. Science. 2017. PMID: 28280149
3D organization of synthetic and scrambled chromosomes.
Mercy G, Mozziconacci J, Scolari VF, Yang K, Zhao G, Thierry A, Luo Y, Mitchell LA, Shen M, Shen Y, Walker R, Zhang W, Wu Y, Xie ZX, Luo Z, Cai Y, Dai J, Yang H, Yuan YJ, Boeke JD, Bader JS, Muller H, Koszul R. Mercy G, et al. Among authors: mitchell la. Science. 2017 Mar 10;355(6329):eaaf4597. doi: 10.1126/science.aaf4597. Science. 2017. PMID: 28280150 Free PMC article.
248 results