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Tumor suppressors miR-143 and miR-145 and predicted target proteins API5, ERK5, K-RAS, and IRS-1 are differentially expressed in proximal and distal colon.
Pekow J, Meckel K, Dougherty U, Butun F, Mustafi R, Lim J, Crofton C, Chen X, Joseph L, Bissonnette M. Pekow J, et al. Among authors: meckel k. Am J Physiol Gastrointest Liver Physiol. 2015 Feb 1;308(3):G179-87. doi: 10.1152/ajpgi.00208.2014. Epub 2014 Dec 4. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 25477374 Free PMC article.
The features of mucosa-associated microbiota in primary sclerosing cholangitis.
Torres J, Bao X, Goel A, Colombel JF, Pekow J, Jabri B, Williams KM, Castillo A, Odin JA, Meckel K, Fasihuddin F, Peter I, Itzkowitz S, Hu J. Torres J, et al. Among authors: meckel k. Aliment Pharmacol Ther. 2016 Apr;43(7):790-801. doi: 10.1111/apt.13552. Epub 2016 Feb 9. Aliment Pharmacol Ther. 2016. PMID: 26857969 Free PMC article.
Serum 25-hydroxyvitamin D concentration is inversely associated with mucosal inflammation in patients with ulcerative colitis.
Meckel K, Li YC, Lim J, Kocherginsky M, Weber C, Almoghrabi A, Chen X, Kaboff A, Sadiq F, Hanauer SB, Cohen RD, Kwon J, Rubin DT, Hanan I, Sakuraba A, Yen E, Bissonnette M, Pekow J. Meckel K, et al. Am J Clin Nutr. 2016 Jul;104(1):113-20. doi: 10.3945/ajcn.115.123786. Epub 2016 Jun 8. Am J Clin Nutr. 2016. PMID: 27281309 Free PMC article.
ADAM17 is a Tumor Promoter and Therapeutic Target in Western Diet-associated Colon Cancer.
Mustafi R, Dougherty U, Mustafi D, Ayaloglu-Butun F, Fletcher M, Adhikari S, Sadiq F, Meckel K, Haider HI, Khalil A, Pekow J, Konda V, Joseph L, Hart J, Fichera A, Li YC, Bissonnette M. Mustafi R, et al. Among authors: meckel k. Clin Cancer Res. 2017 Jan 15;23(2):549-561. doi: 10.1158/1078-0432.CCR-15-3140. Epub 2016 Aug 3. Clin Cancer Res. 2017. PMID: 27489286 Free PMC article.
miR-4728-3p Functions as a Tumor Suppressor in Ulcerative Colitis-associated Colorectal Neoplasia Through Regulation of Focal Adhesion Signaling.
Pekow J, Hutchison AL, Meckel K, Harrington K, Deng Z, Talasila N, Rubin DT, Hanauer SB, Hurst R, Umanskiy K, Fichera A, Hart J, Dinner AR, Bissonnette M. Pekow J, et al. Among authors: meckel k. Inflamm Bowel Dis. 2017 Aug;23(8):1328-1337. doi: 10.1097/MIB.0000000000001104. Inflamm Bowel Dis. 2017. PMID: 28594651 Free PMC article.
miR-193a-3p is a Key Tumor Suppressor in Ulcerative Colitis-Associated Colon Cancer and Promotes Carcinogenesis through Upregulation of IL17RD.
Pekow J, Meckel K, Dougherty U, Huang Y, Chen X, Almoghrabi A, Mustafi R, Ayaloglu-Butun F, Deng Z, Haider HI, Hart J, Rubin DT, Kwon JH, Bissonnette M. Pekow J, et al. Among authors: meckel k. Clin Cancer Res. 2017 Sep 1;23(17):5281-5291. doi: 10.1158/1078-0432.CCR-17-0171. Epub 2017 Jun 9. Clin Cancer Res. 2017. PMID: 28600480 Free PMC article.
Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis Frequently Have Subclinical Inflammation in the Proximal Colon.
Krugliak Cleveland N, Rubin DT, Hart J, Weber CR, Meckel K, Tran AL, Aelvoet AS, Pan I, Gonsalves A, Gaetano JN, Williams KM, Wroblewski K, Jabri B, Pekow J. Krugliak Cleveland N, et al. Among authors: meckel k. Clin Gastroenterol Hepatol. 2018 Jan;16(1):68-74. doi: 10.1016/j.cgh.2017.07.023. Epub 2017 Jul 26. Clin Gastroenterol Hepatol. 2018. PMID: 28756053 Free PMC article.
5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers.
Li W, Zhang X, Lu X, You L, Song Y, Luo Z, Zhang J, Nie J, Zheng W, Xu D, Wang Y, Dong Y, Yu S, Hong J, Shi J, Hao H, Luo F, Hua L, Wang P, Qian X, Yuan F, Wei L, Cui M, Zhang T, Liao Q, Dai M, Liu Z, Chen G, Meckel K, Adhikari S, Jia G, Bissonnette MB, Zhang X, Zhao Y, Zhang W, He C, Liu J. Li W, et al. Among authors: meckel k. Cell Res. 2017 Oct;27(10):1243-1257. doi: 10.1038/cr.2017.121. Epub 2017 Sep 19. Cell Res. 2017. PMID: 28925386 Free PMC article.
51 results