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Molecular signatures order the potency of topically applied anti-inflammatory drugs in patients with atopic dermatitis.
Guttman-Yassky E, Ungar B, Malik K, Dickstein D, Suprun M, Estrada YD, Xu H, Peng X, Oliva M, Todd D, Labuda T, Suarez-Farinas M, Bissonnette R. Guttman-Yassky E, et al. Among authors: malik k. J Allergy Clin Immunol. 2017 Oct;140(4):1032-1042.e13. doi: 10.1016/j.jaci.2017.01.027. Epub 2017 Feb 24. J Allergy Clin Immunol. 2017. PMID: 28238742 Free article. Clinical Trial.
Efficacy and safety of fezakinumab (an IL-22 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by conventional treatments: A randomized, double-blind, phase 2a trial.
Guttman-Yassky E, Brunner PM, Neumann AU, Khattri S, Pavel AB, Malik K, Singer GK, Baum D, Gilleaudeau P, Sullivan-Whalen M, Rose S, Jim On S, Li X, Fuentes-Duculan J, Estrada Y, Garcet S, Traidl-Hoffmann C, Krueger JG, Lebwohl MG. Guttman-Yassky E, et al. Among authors: malik k. J Am Acad Dermatol. 2018 May;78(5):872-881.e6. doi: 10.1016/j.jaad.2018.01.016. Epub 2018 Jan 17. J Am Acad Dermatol. 2018. PMID: 29353025 Free PMC article. Clinical Trial.
Serum from Asian patients with atopic dermatitis is characterized by TH2/TH22 activation, which is highly correlated with nonlesional skin measures.
Wen HC, Czarnowicki T, Noda S, Malik K, Pavel AB, Nakajima S, Honda T, Shin JU, Lee H, Chou M, Estrada Y, Zheng X, Xu H, Krueger JG, Lee KH, Kabashima K, Guttman-Yassky E. Wen HC, et al. Among authors: malik k. J Allergy Clin Immunol. 2018 Jul;142(1):324-328.e11. doi: 10.1016/j.jaci.2018.02.047. Epub 2018 Apr 11. J Allergy Clin Immunol. 2018. PMID: 29653116 No abstract available.
Baseline IL-22 expression in patients with atopic dermatitis stratifies tissue responses to fezakinumab.
Brunner PM, Pavel AB, Khattri S, Leonard A, Malik K, Rose S, Jim On S, Vekaria AS, Traidl-Hoffmann C, Singer GK, Baum D, Gilleaudeau P, Sullivan-Whalen M, Fuentes-Duculan J, Li X, Zheng X, Estrada Y, Garcet S, Wen HC, Gonzalez J, Coats I, Cueto I, Neumann AU, Lebwohl MG, Krueger JG, Guttman-Yassky E. Brunner PM, et al. Among authors: malik k. J Allergy Clin Immunol. 2019 Jan;143(1):142-154. doi: 10.1016/j.jaci.2018.07.028. Epub 2018 Aug 17. J Allergy Clin Immunol. 2019. PMID: 30121291 Clinical Trial.
Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
Zhou L, Leonard A, Pavel AB, Malik K, Raja A, Glickman J, Estrada YD, Peng X, Del Duca E, Sanz-Cabanillas J, Ruano J, Xu H, Zhang N, Wen HC, Gonzalez J, Garcet S, Krueger JG, Guttman-Yassky E. Zhou L, et al. Among authors: malik k. J Allergy Clin Immunol. 2019 Jul;144(1):144-156. doi: 10.1016/j.jaci.2019.01.015. Epub 2019 Jan 24. J Allergy Clin Immunol. 2019. PMID: 30685456 Free article.
The blood proteomic signature of early-onset pediatric atopic dermatitis shows systemic inflammation and is distinct from adult long-standing disease.
Brunner PM, He H, Pavel AB, Czarnowicki T, Lefferdink R, Erickson T, Canter T, Puar N, Rangel SM, Malik K, Estrada Y, Krueger JG, Guttman-Yassky E, Paller AS. Brunner PM, et al. Among authors: malik k. J Am Acad Dermatol. 2019 Aug;81(2):510-519. doi: 10.1016/j.jaad.2019.04.036. Epub 2019 Apr 19. J Am Acad Dermatol. 2019. PMID: 31009665
Dust mite induces multiple polar T cell axes in human skin.
Malik K, Ungar B, Garcet S, Dutt R, Dickstein D, Zheng X, Xu H, Estrada YD, Suárez-Fariñas M, Shemer A, Krueger JG, Guttman-Yassky E. Malik K, et al. Clin Exp Allergy. 2017 Dec;47(12):1648-1660. doi: 10.1111/cea.13040. Epub 2017 Nov 6. Clin Exp Allergy. 2017. PMID: 28977706
1,043 results