Lai HT - Search Results

1

Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration.

Bao L, Chen Y, Lai HT, Wu SY, Wang JE, Hatanpaa KJ, Raisanen JM, Fontenot M, Lega B, Chiang CM, Semenza GL, Wang Y, Luo W. Bao L, et al. Among authors: lai ht. Nucleic Acids Res. 2018 Jul 27;46(13):6576-6591. doi: 10.1093/nar/gky449. Nucleic Acids Res. 2018. PMID: 29860315 Free PMC article.

2

Phospho switch triggers Brd4 chromatin binding and activator recruitment for gene-specific targeting.

Wu SY, Lee AY, Lai HT, Zhang H, Chiang CM. Wu SY, et al. Among authors: lai ht. Mol Cell. 2013 Mar 7;49(5):843-57. doi: 10.1016/j.molcel.2012.12.006. Epub 2013 Jan 11. Mol Cell. 2013. PMID: 23317504 Free PMC article.

3

Bimolecular Fluorescence Complementation (BiFC) Assay for Direct Visualization of Protein-Protein Interaction in vivo.

Lai HT, Chiang CM. Lai HT, et al. Bio Protoc. 2013;3(20):e935. doi: 10.21769/bioprotoc.935. Epub 2013 Oct 20. Bio Protoc. 2013. PMID: 27390756 Free PMC article.

4

Opposing Functions of BRD4 Isoforms in Breast Cancer.

Wu SY, Lee CF, Lai HT, Yu CT, Lee JE, Zuo H, Tsai SY, Tsai MJ, Ge K, Wan Y, Chiang CM. Wu SY, et al. Among authors: lai ht. Mol Cell. 2020 Jun 18;78(6):1114-1132.e10. doi: 10.1016/j.molcel.2020.04.034. Epub 2020 May 23. Mol Cell. 2020. PMID: 32446320 Free PMC article.

5

Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site.

Liu Z, Li Y, Chen H, Lai HT, Wang P, Wu SY, Wold EA, Leonard PG, Joseph S, Hu H, Chiang CM, Brasier AR, Tian B, Zhou J. Liu Z, et al. Among authors: lai ht. J Med Chem. 2022 Feb 10;65(3):2388-2408. doi: 10.1021/acs.jmedchem.1c01851. Epub 2022 Jan 4. J Med Chem. 2022. PMID: 34982556 Free PMC article.

6

IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors.

Wu SY, Lai HT, Sanjib Banerjee N, Ma Z, Santana JF, Wei S, Liu X, Zhang M, Zhan J, Chen H, Posner B, Chen Y, Price DH, Chow LT, Zhou J, Chiang CM. Wu SY, et al. Among authors: lai ht. Mol Cell. 2024 Jan 18;84(2):202-220.e15. doi: 10.1016/j.molcel.2023.11.022. Epub 2023 Dec 15. Mol Cell. 2024. PMID: 38103559

7

Novel BRD4-p53 Inhibitor SDU-071 Suppresses Proliferation and Migration of MDA-MB-231 Triple-Negative Breast Cancer Cells.

Wang S, Lei K, Lai HT, Liu T, Du L, Wu SY, Ye X, Chiang CM, Li M. Wang S, et al. Among authors: lai ht. ACS Pharmacol Transl Sci. 2024 Mar 12;7(4):1178-1190. doi: 10.1021/acsptsci.4c00057. eCollection 2024 Apr 12. ACS Pharmacol Transl Sci. 2024. PMID: 38633583

8

Trimethylamine N-Oxide and Related Gut Microbe-Derived Metabolites and Incident Heart Failure Development in Community-Based Populations.

Tang WHW, Lemaitre RN, Jensen PN, Wang M, Wang Z, Li XS, Nemet I, Lee Y, Lai HTM, de Oliveira Otto MC, Fretts AM, Sotoodehnia N, DiDonato JA, Bäckhed F, Psaty BM, Siscovick DS, Budoff MJ, Mozaffarian D, Hazen SL. Tang WHW, et al. Among authors: lai htm. Circ Heart Fail. 2024 Aug;17(8):e011569. doi: 10.1161/CIRCHEARTFAILURE.124.011569. Epub 2024 Aug 9. Circ Heart Fail. 2024. PMID: 39119698

9

Treating waste with waste: adsorption behavior and mechanism of phosphate in water by modified phosphogypsum biochar.

Shan LL, Wang RS, Lai HT, Zhu ZB, Chen Y, Ni ZY, Pang CL, Zhang QZ. Shan LL, et al. Among authors: lai ht. Environ Sci Pollut Res Int. 2024 Aug;31(38):50411-50426. doi: 10.1007/s11356-024-34272-z. Epub 2024 Aug 2. Environ Sci Pollut Res Int. 2024. PMID: 39093397

10

Nrf2 Signaling Pathway: Focus on Oxidative Stress in Spinal Cord Injury.

Xiao CL, Lai HT, Zhou JJ, Liu WY, Zhao M, Zhao K. Xiao CL, et al. Among authors: lai ht. Mol Neurobiol. 2024 Aug 2. doi: 10.1007/s12035-024-04394-z. Online ahead of print. Mol Neurobiol. 2024. PMID: 39093381 Review.

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