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Page 1
Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres.
Otto TD, Böhme U, Sanders M, Reid A, Bruske EI, Duffy CW, Bull PC, Pearson RD, Abdi A, Dimonte S, Stewart LB, Campino S, Kekre M, Hamilton WL, Claessens A, Volkman SK, Ndiaye D, Amambua-Ngwa A, Diakite M, Fairhurst RM, Conway DJ, Franck M, Newbold CI, Berriman M. Otto TD, et al. Among authors: hamilton wl. Wellcome Open Res. 2018 May 3;3:52. doi: 10.12688/wellcomeopenres.14571.1. eCollection 2018. Wellcome Open Res. 2018. PMID: 29862326 Free PMC article.
Optimized whole-genome amplification strategy for extremely AT-biased template.
Oyola SO, Manske M, Campino S, Claessens A, Hamilton WL, Kekre M, Drury E, Mead D, Gu Y, Miles A, MacInnis B, Newbold C, Berriman M, Kwiatkowski DP. Oyola SO, et al. Among authors: hamilton wl. DNA Res. 2014 Dec;21(6):661-71. doi: 10.1093/dnares/dsu028. Epub 2014 Sep 19. DNA Res. 2014. PMID: 25240466 Free PMC article.
Extreme mutation bias and high AT content in Plasmodium falciparum.
Hamilton WL, Claessens A, Otto TD, Kekre M, Fairhurst RM, Rayner JC, Kwiatkowski D. Hamilton WL, et al. Nucleic Acids Res. 2017 Feb 28;45(4):1889-1901. doi: 10.1093/nar/gkw1259. Nucleic Acids Res. 2017. PMID: 27994033 Free PMC article.
Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification.
Oyola SO, Ariani CV, Hamilton WL, Kekre M, Amenga-Etego LN, Ghansah A, Rutledge GG, Redmond S, Manske M, Jyothi D, Jacob CG, Otto TD, Rockett K, Newbold CI, Berriman M, Kwiatkowski DP. Oyola SO, et al. Among authors: hamilton wl. Malar J. 2016 Dec 20;15(1):597. doi: 10.1186/s12936-016-1641-7. Malar J. 2016. PMID: 27998271 Free PMC article.
Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study.
Hamilton WL, Amato R, van der Pluijm RW, Jacob CG, Quang HH, Thuy-Nhien NT, Hien TT, Hongvanthong B, Chindavongsa K, Mayxay M, Huy R, Leang R, Huch C, Dysoley L, Amaratunga C, Suon S, Fairhurst RM, Tripura R, Peto TJ, Sovann Y, Jittamala P, Hanboonkunupakarn B, Pukrittayakamee S, Chau NH, Imwong M, Dhorda M, Vongpromek R, Chan XHS, Maude RJ, Pearson RD, Nguyen T, Rockett K, Drury E, Gonçalves S, White NJ, Day NP, Kwiatkowski DP, Dondorp AM, Miotto O. Hamilton WL, et al. Lancet Infect Dis. 2019 Sep;19(9):943-951. doi: 10.1016/S1473-3099(19)30392-5. Epub 2019 Jul 22. Lancet Infect Dis. 2019. PMID: 31345709 Free PMC article.
Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study.
van der Pluijm RW, Imwong M, Chau NH, Hoa NT, Thuy-Nhien NT, Thanh NV, Jittamala P, Hanboonkunupakarn B, Chutasmit K, Saelow C, Runjarern R, Kaewmok W, Tripura R, Peto TJ, Yok S, Suon S, Sreng S, Mao S, Oun S, Yen S, Amaratunga C, Lek D, Huy R, Dhorda M, Chotivanich K, Ashley EA, Mukaka M, Waithira N, Cheah PY, Maude RJ, Amato R, Pearson RD, Gonçalves S, Jacob CG, Hamilton WL, Fairhurst RM, Tarning J, Winterberg M, Kwiatkowski DP, Pukrittayakamee S, Hien TT, Day NP, Miotto O, White NJ, Dondorp AM. van der Pluijm RW, et al. Among authors: hamilton wl. Lancet Infect Dis. 2019 Sep;19(9):952-961. doi: 10.1016/S1473-3099(19)30391-3. Epub 2019 Jul 22. Lancet Infect Dis. 2019. PMID: 31345710 Free PMC article. Clinical Trial.
An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples.
MalariaGEN; Ahouidi A, Ali M, Almagro-Garcia J, Amambua-Ngwa A, Amaratunga C, Amato R, Amenga-Etego L, Andagalu B, Anderson TJC, Andrianaranjaka V, Apinjoh T, Ariani C, Ashley EA, Auburn S, Awandare GA, Ba H, Baraka V, Barry AE, Bejon P, Bertin GI, Boni MF, Borrmann S, Bousema T, Branch O, Bull PC, Busby GBJ, Chookajorn T, Chotivanich K, Claessens A, Conway D, Craig A, D'Alessandro U, Dama S, Day NP, Denis B, Diakite M, Djimdé A, Dolecek C, Dondorp AM, Drakeley C, Drury E, Duffy P, Echeverry DF, Egwang TG, Erko B, Fairhurst RM, Faiz A, Fanello CA, Fukuda MM, Gamboa D, Ghansah A, Golassa L, Goncalves S, Hamilton WL, Harrison GLA, Hart L, Henrichs C, Hien TT, Hill CA, Hodgson A, Hubbart C, Imwong M, Ishengoma DS, Jackson SA, Jacob CG, Jeffery B, Jeffreys AE, Johnson KJ, Jyothi D, Kamaliddin C, Kamau E, Kekre M, Kluczynski K, Kochakarn T, Konaté A, Kwiatkowski DP, Kyaw MP, Lim P, Lon C, Loua KM, Maïga-Ascofaré O, Malangone C, Manske M, Marfurt J, Marsh K, Mayxay M, Miles A, Miotto O, Mobegi V, Mokuolu OA, Montgomery J, Mueller I, Newton PN, Nguyen T, Nguyen TN, Noedl H, Nosten F, Noviyanti R, Nzila A, Ochola-Oyier LI, Ocholla H, Oduro A, Omedo I, Onyamboko MA, Ouedraogo JB, Oy… See abstract for full author list ➔ MalariaGEN, et al. Among authors: hamilton wl. Wellcome Open Res. 2021 Jul 13;6:42. doi: 10.12688/wellcomeopenres.16168.2. eCollection 2021. Wellcome Open Res. 2021. PMID: 33824913 Free PMC article.
Identification of complex Plasmodium falciparum genetic backgrounds circulating in Africa: a multicountry genomic epidemiology analysis.
Miotto O, Amambua-Ngwa A, Amenga-Etego LN, Abdel Hamid MM, Adam I, Aninagyei E, Apinjoh T, Awandare GA, Bejon P, Bertin GI, Bouyou-Akotet M, Claessens A, Conway DJ, D'Alessandro U, Diakite M, Djimdé A, Dondorp AM, Duffy P, Fairhurst RM, Fanello CI, Ghansah A, Ishengoma DS, Lawniczak M, Maïga-Ascofaré O, Auburn S, Rosanas-Urgell A, Wasakul V, White NFD, Harrott A, Almagro-Garcia J, Pearson RD, Goncalves S, Ariani C, Bozdech Z, Hamilton WL, Simpson V, Kwiatkowski DP. Miotto O, et al. Among authors: hamilton wl. Lancet Microbe. 2024 Dec;5(12):100941. doi: 10.1016/j.lanmic.2024.07.004. Epub 2024 Nov 7. Lancet Microbe. 2024. PMID: 39522520 Free PMC article.
Drug resistance and vaccine target surveillance of Plasmodium falciparum using nanopore sequencing in Ghana.
Girgis ST, Adika E, Nenyewodey FE, Senoo Jnr DK, Ngoi JM, Bandoh K, Lorenz O, van de Steeg G, Harrott AJR, Nsoh S, Judge K, Pearson RD, Almagro-Garcia J, Saiid S, Atampah S, Amoako EK, Morang'a CM, Asoala V, Adjei ES, Burden W, Roberts-Sengier W, Drury E, Pierce ML, Gonçalves S, Awandare GA, Kwiatkowski DP, Amenga-Etego LN, Hamilton WL. Girgis ST, et al. Among authors: hamilton wl. Nat Microbiol. 2023 Dec;8(12):2365-2377. doi: 10.1038/s41564-023-01516-6. Epub 2023 Nov 23. Nat Microbiol. 2023. PMID: 37996707 Free PMC article.
76 results