Minor L - Search Results

1

Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery.

Coussens NP, Sittampalam GS, Guha R, Brimacombe K, Grossman A, Chung TDY, Weidner JR, Riss T, Trask OJ, Auld D, Dahlin JL, Devanaryan V, Foley TL, McGee J, Kahl SD, Kales SC, Arkin M, Baell J, Bejcek B, Gal-Edd N, Glicksman M, Haas JV, Iversen PW, Hoeppner M, Lathrop S, Sayers E, Liu H, Trawick B, McVey J, Lemmon VP, Li Z, McManus O, Minor L, Napper A, Wildey MJ, Pacifici R, Chin WW, Xia M, Xu X, Lal-Nag M, Hall MD, Michael S, Inglese J, Simeonov A, Austin CP. Coussens NP, et al. Among authors: minor l. Clin Transl Sci. 2018 Sep;11(5):461-470. doi: 10.1111/cts.12570. Epub 2018 Jul 24. Clin Transl Sci. 2018. PMID: 29877628 Free PMC article. Review.

2

Validation of a cell-based screen for insulin receptor modulators by quantification of insulin receptor phosphorylation.

Minor LK, Westover L, Kong Y, Patel D, Wildey MJ, Conway BR, Demarest KT. Minor LK, et al. J Biomol Screen. 2003 Aug;8(4):439-46. doi: 10.1177/1087057103255280. J Biomol Screen. 2003. PMID: 14567796

3

Virus-based expression systems facilitate rapid target in vivo functionality validation and high-throughput screening.

Darrow AL, Conway KA, Vaidya AH, Rosenthal D, Wildey MJ, Minor L, Itkin Z, Kong Y, Piesvaux J, Qi J, Mercken M, Andrade-Gordon P, Plata-Salamán C, Ilyin SE. Darrow AL, et al. Among authors: minor l. J Biomol Screen. 2003 Feb;8(1):65-71. doi: 10.1177/1087057102239664. J Biomol Screen. 2003. PMID: 12854999

4

Cell-based, high-content screen for receptor internalization, recycling and intracellular trafficking.

Ghosh RN, Chen YT, DeBiasio R, DeBiasio RL, Conway BR, Minor LK, Demarest KT. Ghosh RN, et al. Among authors: minor lk. Biotechniques. 2000 Jul;29(1):170-5. doi: 10.2144/00291pf01. Biotechniques. 2000. PMID: 10907092 Free article.

5

Quantitative analysis of agonist-dependent parathyroid hormone receptor trafficking in whole cells using a functional green fluorescent protein conjugate.

Conway BR, Minor LK, Xu JZ, D'Andrea MR, Ghosh RN, Demarest KT. Conway BR, et al. Among authors: minor lk. J Cell Physiol. 2001 Dec;189(3):341-55. doi: 10.1002/jcp.10028. J Cell Physiol. 2001. PMID: 11748592

6

A branched DNA signal amplification assay to quantitate messenger RNA of human uncoupling proteins 1, 2, and 3.

Zhou L, Cryan EV, Minor LK, Gunnet JW, Demarest KT. Zhou L, et al. Among authors: minor lk. Anal Biochem. 2000 Jun 15;282(1):46-53. doi: 10.1006/abio.2000.4587. Anal Biochem. 2000. PMID: 10860498

7

Next-generation spirobenzazepines: identification of RWJ-676070 as a balanced vasopressin V1a/V2 receptor antagonist for human clinical studies.

Xiang MA, Rybczynski PJ, Patel M, Chen RH, McComsey DF, Zhang HC, Gunnet JW, Look R, Wang Y, Minor LK, Zhong HM, Villani FJ, Demarest KT, Damiano BP, Maryanoff BE. Xiang MA, et al. Bioorg Med Chem Lett. 2007 Dec 1;17(23):6623-8. doi: 10.1016/j.bmcl.2007.09.059. Epub 2007 Sep 19. Bioorg Med Chem Lett. 2007. PMID: 17942308

8

High-content assays for evaluating cellular and hepatic diacylglycerol acyltransferase activity.

Qi J, Lang W, Giardino E, Caldwell GW, Smith C, Minor LK, Darrow AL, Willemsens G, Dewaepenaert K, Roevens P, Linders JT, Liang Y, Connelly MA. Qi J, et al. Among authors: minor lk. J Lipid Res. 2010 Dec;51(12):3559-67. doi: 10.1194/jlr.D008029. Epub 2010 Aug 28. J Lipid Res. 2010. PMID: 20805092 Free PMC article.

9

Characterization of functional urotensin II receptors in human skeletal muscle myoblasts: comparison with angiotensin II receptors.

Qi JS, Minor LK, Smith C, Hu B, Yang J, Andrade-Gordon P, Damiano B. Qi JS, et al. Peptides. 2005 Apr;26(4):683-90. doi: 10.1016/j.peptides.2004.11.018. Epub 2005 Jan 1. Peptides. 2005. PMID: 15752584

10

Pharmacological characterization of RWJ-676070, a dual vasopressin V(1A)/V(2) receptor antagonist.

Gunnet JW, Wines P, Xiang M, Rybczynski P, Andrade-Gordon P, de Garavilla L, Parry TJ, Cheung WM, Minor L, Demarest KT, Maryanoff BE, Damiano BP. Gunnet JW, et al. Among authors: minor l. Eur J Pharmacol. 2008 Aug 20;590(1-3):333-42. doi: 10.1016/j.ejphar.2008.06.010. Epub 2008 Jun 7. Eur J Pharmacol. 2008. PMID: 18599033

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