Imae R - Search Results

1

CDP-glycerol inhibits the synthesis of the functional O-mannosyl glycan of α-dystroglycan.

Imae R, Manya H, Tsumoto H, Osumi K, Tanaka T, Mizuno M, Kanagawa M, Kobayashi K, Toda T, Endo T. Imae R, et al. J Biol Chem. 2018 Aug 3;293(31):12186-12198. doi: 10.1074/jbc.RA118.003197. Epub 2018 Jun 8. J Biol Chem. 2018. PMID: 29884773 Free PMC article.

2

Cell endogenous activities of fukutin and FKRP coexist with the ribitol xylosyltransferase, TMEM5.

Nishihara R, Kobayashi K, Imae R, Tsumoto H, Manya H, Mizuno M, Kanagawa M, Endo T, Toda T. Nishihara R, et al. Among authors: imae r. Biochem Biophys Res Commun. 2018 Mar 18;497(4):1025-1030. doi: 10.1016/j.bbrc.2018.02.162. Biochem Biophys Res Commun. 2018. PMID: 29477842

3

Crystal structures of fukutin-related protein (FKRP), a ribitol-phosphate transferase related to muscular dystrophy.

Kuwabara N, Imae R, Manya H, Tanaka T, Mizuno M, Tsumoto H, Kanagawa M, Kobayashi K, Toda T, Senda T, Endo T, Kato R. Kuwabara N, et al. Among authors: imae r. Nat Commun. 2020 Jan 16;11(1):303. doi: 10.1038/s41467-019-14220-z. Nat Commun. 2020. PMID: 31949166 Free PMC article.

4

The structure of POMGNT2 provides new insights into the mechanism to determine the functional O-mannosylation site on α-dystroglycan.

Imae R, Kuwabara N, Manya H, Tanaka T, Tsuyuguchi M, Mizuno M, Endo T, Kato R. Imae R, et al. Genes Cells. 2021 Jul;26(7):485-494. doi: 10.1111/gtc.12853. Epub 2021 May 20. Genes Cells. 2021. PMID: 33893702 Free PMC article.

5

PCYT2 synthesizes CDP-glycerol in mammals and reduced PCYT2 enhances the expression of functionally glycosylated α-dystroglycan.

Imae R, Manya H, Tsumoto H, Miura Y, Endo T. Imae R, et al. J Biochem. 2021 Oct 11;170(2):183-194. doi: 10.1093/jb/mvab069. J Biochem. 2021. PMID: 34255834

6

Biosynthetic Mechanisms and Biological Significance of Glycerol Phosphate-Containing Glycan in Mammals.

Imae R, Manya H, Endo T. Imae R, et al. Molecules. 2021 Nov 4;26(21):6675. doi: 10.3390/molecules26216675. Molecules. 2021. PMID: 34771084 Free PMC article. Review.

7

CDP-ribitol prodrug treatment ameliorates ISPD-deficient muscular dystrophy mouse model.

Tokuoka H, Imae R, Nakashima H, Manya H, Masuda C, Hoshino S, Kobayashi K, Lefeber DJ, Matsumoto R, Okada T, Endo T, Kanagawa M, Toda T. Tokuoka H, et al. Among authors: imae r. Nat Commun. 2022 Apr 14;13(1):1847. doi: 10.1038/s41467-022-29473-4. Nat Commun. 2022. PMID: 35422047 Free PMC article.

8

Chemical and Chemo-Enzymatic Syntheses of Glycans Containing Ribitol Phosphate Scaffolding of Matriglycan.

Tamura JI, Tamura T, Hoshino S, Imae R, Kato R, Yokono M, Nagase M, Ohno S, Manabe N, Yamaguchi Y, Manya H, Endo T. Tamura JI, et al. Among authors: imae r. ACS Chem Biol. 2022 Jun 17;17(6):1513-1523. doi: 10.1021/acschembio.2c00181. Epub 2022 Jun 6. ACS Chem Biol. 2022. PMID: 35670527

9

Endogenous reductase activities for the generation of ribitol-phosphate, a CDP-ribitol precursor, in mammals.

Hoshino S, Manya H, Imae R, Kobayashi K, Kanagawa M, Endo T. Hoshino S, et al. Among authors: imae r. J Biochem. 2024 Mar 25;175(4):418-425. doi: 10.1093/jb/mvad115. J Biochem. 2024. PMID: 38140954

10

Changes in the amount of nucleotide sugars in aged mouse tissues.

Imae R, Manya H, Tsumoto H, Umezawa K, Miura Y, Endo T. Imae R, et al. Glycobiology. 2024 Apr 24;34(6):cwae032. doi: 10.1093/glycob/cwae032. Glycobiology. 2024. PMID: 38598324

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