Bao Y - Search Results

1

Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer.

Tang YA, Chen YF, Bao Y, Mahara S, Yatim SMJM, Oguz G, Lee PL, Feng M, Cai Y, Tan EY, Fong SS, Yang ZH, Lan P, Wu XJ, Yu Q. Tang YA, et al. Among authors: bao y. Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E5990-E5999. doi: 10.1073/pnas.1801348115. Epub 2018 Jun 11. Proc Natl Acad Sci U S A. 2018. PMID: 29891662 Free PMC article.

2

RASAL2 activates RAC1 to promote triple-negative breast cancer progression.

Feng M, Bao Y, Li Z, Li J, Gong M, Lam S, Wang J, Marzese DM, Donovan N, Tan EY, Hoon DS, Yu Q. Feng M, et al. Among authors: bao y. J Clin Invest. 2014 Dec;124(12):5291-304. doi: 10.1172/JCI76711. Epub 2014 Nov 10. J Clin Invest. 2014. PMID: 25384218 Free PMC article. Clinical Trial.

3

IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel.

Wee ZN, Yatim SM, Kohlbauer VK, Feng M, Goh JY, Bao Y, Lee PL, Zhang S, Wang PP, Lim E, Tam WL, Cai Y, Ditzel HJ, Hoon DS, Tan EY, Yu Q. Wee ZN, et al. Among authors: bao y. Nat Commun. 2015 Oct 27;6:8746. doi: 10.1038/ncomms9746. Nat Commun. 2015. PMID: 26503059 Free PMC article.

4

Corrigendum: IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel.

Wee ZN, Yatim SMJM, Kohlabauer VK, Feng M, Goh JY, Bao Y, Lee PL, Zhang S, Wang PP, Lim E, Tam WL, Cai Y, Ditzel HJ, Hoon DSB, Tan EY, Yu Q. Wee ZN, et al. Among authors: bao y. Nat Commun. 2015 Nov 20;6:10054. doi: 10.1038/ncomms10054. Nat Commun. 2015. PMID: 26585835 Free PMC article. No abstract available.

5

Chromosome 1q21.3 amplification is a trackable biomarker and actionable target for breast cancer recurrence.

Goh JY, Feng M, Wang W, Oguz G, Yatim SMJM, Lee PL, Bao Y, Lim TH, Wang P, Tam WL, Kodahl AR, Lyng MB, Sarma S, Lin SY, Lezhava A, Yap YS, Lim AST, Hoon DSB, Ditzel HJ, Lee SC, Tan EY, Yu Q. Goh JY, et al. Among authors: bao y. Nat Med. 2017 Nov;23(11):1319-1330. doi: 10.1038/nm.4405. Epub 2017 Sep 25. Nat Med. 2017. PMID: 28967919

6

KDM6B Counteracts EZH2-Mediated Suppression of IGFBP5 to Confer Resistance to PI3K/AKT Inhibitor Treatment in Breast Cancer.

Wang W, Lim KG, Feng M, Bao Y, Lee PL, Cai Y, Chen Y, Zhang H, Marzese D, Hoon DSB, Yu Q. Wang W, et al. Among authors: bao y. Mol Cancer Ther. 2018 Sep;17(9):1973-1983. doi: 10.1158/1535-7163.MCT-17-0802. Epub 2018 Jun 20. Mol Cancer Ther. 2018. PMID: 29925528

7

KDM4B-regulated unfolded protein response as a therapeutic vulnerability in PTEN-deficient breast cancer.

Wang W, Oguz G, Lee PL, Bao Y, Wang P, Terp MG, Ditzel HJ, Yu Q. Wang W, et al. Among authors: bao y. J Exp Med. 2018 Nov 5;215(11):2833-2849. doi: 10.1084/jem.20180439. Epub 2018 Sep 28. J Exp Med. 2018. PMID: 30266800 Free PMC article.

8

HER2-L755S mutation induces hyperactive MAPK and PI3K-mTOR signaling, leading to resistance to HER2 tyrosine kinase inhibitor treatment.

Li J, Xiao Q, Bao Y, Wang W, Goh J, Wang P, Yu Q. Li J, et al. Among authors: bao y. Cell Cycle. 2019 Jul;18(13):1513-1522. doi: 10.1080/15384101.2019.1624113. Epub 2019 Jun 3. Cell Cycle. 2019. PMID: 31135266 Free PMC article.

9

EZH2-mediated PP2A inactivation confers resistance to HER2-targeted breast cancer therapy.

Bao Y, Oguz G, Lee WC, Lee PL, Ghosh K, Li J, Wang P, Lobie PE, Ehmsen S, Ditzel HJ, Wong A, Tan EY, Lee SC, Yu Q. Bao Y, et al. Nat Commun. 2020 Nov 18;11(1):5878. doi: 10.1038/s41467-020-19704-x. Nat Commun. 2020. PMID: 33208750 Free PMC article.

10

IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer.

Ong LT, Lee WC, Ma S, Oguz G, Niu Z, Bao Y, Yusuf M, Lee PL, Goh JY, Wang P, Yong KSM, Chen Q, Wang W, Ramasamy A, Hoon DSB, Ditzel HJ, Tan EY, Lee SC, Yu Q. Ong LT, et al. Among authors: bao y. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2201376119. doi: 10.1073/pnas.2201376119. Epub 2022 Jul 25. Proc Natl Acad Sci U S A. 2022. PMID: 35878022 Free PMC article.

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