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Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation.
Jacobs J, Deschoolmeester V, Zwaenepoel K, Flieswasser T, Deben C, Van den Bossche J, Hermans C, Rolfo C, Peeters M, De Wever O, Lardon F, Siozopoulou V, Smits E, Pauwels P. Jacobs J, et al. Among authors: hermans c. Oncoimmunology. 2018 Mar 19;7(7):e1440167. doi: 10.1080/2162402X.2018.1440167. eCollection 2018. Oncoimmunology. 2018. PMID: 29900042 Free PMC article.
Deep sequencing of the TP53 gene reveals a potential risk allele for non-small cell lung cancer and supports the negative prognostic value of TP53 variants.
Deben C, Van den Bossche J, Van Der Steen N, Lardon F, Wouters A, de Beeck KO, Hermans C, Jacobs J, Peeters M, Van Camp G, Rolfo C, Deschoolmeester V, Pauwels P. Deben C, et al. Among authors: hermans c. Tumour Biol. 2017 Feb;39(2):1010428317694327. doi: 10.1177/1010428317694327. Tumour Biol. 2017. PMID: 28240049 Free article.
Towards Prognostic Profiling of Non-Small Cell Lung Cancer: New Perspectives on the Relevance of Polo-Like Kinase 1 Expression, the TP53 Mutation Status and Hypoxia.
Van den Bossche J, Deben C, Op de Beeck K, Deschoolmeester V, Hermans C, De Pauw I, Jacobs J, Van Schil P, Vermorken JB, Pauwels P, Peeters M, Lardon F, Wouters A. Van den Bossche J, et al. Among authors: hermans c. J Cancer. 2017 May 12;8(8):1441-1452. doi: 10.7150/jca.18455. eCollection 2017. J Cancer. 2017. PMID: 28638459 Free PMC article.
Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy.
Jacobs J, Deschoolmeester V, Rolfo C, Zwaenepoel K, Van den Bossche J, Deben C, Silence K, de Haard H, Hermans C, Rottey S, Vangestel C, Lardon F, Smits E, Pauwels P. Jacobs J, et al. Among authors: hermans c. Oncotarget. 2017 May 23;8(43):74058-74067. doi: 10.18632/oncotarget.18202. eCollection 2017 Sep 26. Oncotarget. 2017. PMID: 29088768 Free PMC article.
In vitro study of the Polo-like kinase 1 inhibitor volasertib in non-small-cell lung cancer reveals a role for the tumor suppressor p53.
Van den Bossche J, Deben C, De Pauw I, Lambrechts H, Hermans C, Deschoolmeester V, Jacobs J, Specenier P, Pauwels P, Vermorken JB, Peeters M, Lardon F, Wouters A. Van den Bossche J, et al. Among authors: hermans c. Mol Oncol. 2019 May;13(5):1196-1213. doi: 10.1002/1878-0261.12477. Epub 2019 Apr 5. Mol Oncol. 2019. PMID: 30859681 Free PMC article.
Desmoid tumors display a strong immune infiltration at the tumor margins and no PD-L1-driven immune suppression.
Siozopoulou V, Marcq E, Jacobs J, Zwaenepoel K, Hermans C, Brauns J, Pauwels S, Huysentruyt C, Lammens M, Somville J, Smits E, Pauwels P. Siozopoulou V, et al. Among authors: hermans c. Cancer Immunol Immunother. 2019 Oct;68(10):1573-1583. doi: 10.1007/s00262-019-02390-0. Epub 2019 Sep 11. Cancer Immunol Immunother. 2019. PMID: 31511925 Free PMC article.
Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer.
Freire Boullosa L, Van Loenhout J, Flieswasser T, De Waele J, Hermans C, Lambrechts H, Cuypers B, Laukens K, Bartholomeus E, Siozopoulou V, De Vos WH, Peeters M, Smits ELJ, Deben C. Freire Boullosa L, et al. Among authors: hermans c. Redox Biol. 2021 Jun;42:101949. doi: 10.1016/j.redox.2021.101949. Epub 2021 Mar 19. Redox Biol. 2021. PMID: 33812801 Free PMC article.
Expression of SARS-CoV-2-Related Surface Proteins in Non-Small-Cell Lung Cancer Patients and the Influence of Standard of Care Therapy.
Deben C, Le Compte M, Siozopoulou V, Lambrechts H, Hermans C, Lau HW, Huizing M, Lamote K, Hendriks JMH, Van Dam P, Pauwels P, Smits ELJ, Peeters M, Lardon F. Deben C, et al. Among authors: hermans c. Cancers (Basel). 2022 Aug 23;14(17):4074. doi: 10.3390/cancers14174074. Cancers (Basel). 2022. PMID: 36077610 Free PMC article.
563 results