Lerman LS - Search Results

1

A general method for saturation mutagenesis of cloned DNA fragments.

Myers RM, Lerman LS, Maniatis T. Myers RM, et al. Among authors: lerman ls. Science. 1985 Jul 19;229(4710):242-7. doi: 10.1126/science.2990046. Science. 1985. PMID: 2990046

2

Modification of the melting properties of duplex DNA by attachment of a GC-rich DNA sequence as determined by denaturing gradient gel electrophoresis.

Myers RM, Fischer SG, Maniatis T, Lerman LS. Myers RM, et al. Among authors: lerman ls. Nucleic Acids Res. 1985 May 10;13(9):3111-29. doi: 10.1093/nar/13.9.3111. Nucleic Acids Res. 1985. PMID: 2987873 Free PMC article.

3

Detection of single base substitutions in total genomic DNA.

Myers RM, Lumelsky N, Lerman LS, Maniatis T. Myers RM, et al. Among authors: lerman ls. Nature. 1985 Feb 7-13;313(6002):495-8. doi: 10.1038/313495a0. Nature. 1985. PMID: 3969155

4

Nearly all single base substitutions in DNA fragments joined to a GC-clamp can be detected by denaturing gradient gel electrophoresis.

Myers RM, Fischer SG, Lerman LS, Maniatis T. Myers RM, et al. Among authors: lerman ls. Nucleic Acids Res. 1985 May 10;13(9):3131-45. doi: 10.1093/nar/13.9.3131. Nucleic Acids Res. 1985. PMID: 4000972 Free PMC article.

5

Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes.

Sheffield VC, Cox DR, Lerman LS, Myers RM. Sheffield VC, et al. Among authors: lerman ls. Proc Natl Acad Sci U S A. 1989 Jan;86(1):232-6. doi: 10.1073/pnas.86.1.232. Proc Natl Acad Sci U S A. 1989. PMID: 2643100 Free PMC article.

6

Detection and localization of single base changes by denaturing gradient gel electrophoresis.

Myers RM, Maniatis T, Lerman LS. Myers RM, et al. Among authors: lerman ls. Methods Enzymol. 1987;155:501-27. doi: 10.1016/0076-6879(87)55033-9. Methods Enzymol. 1987. PMID: 3431470 No abstract available.

7

The structure of psi DNA.

Maniatis T, Venable JH Jr, Lerman LS. Maniatis T, et al. Among authors: lerman ls. J Mol Biol. 1974 Mar 25;84(1):37-64. doi: 10.1016/0022-2836(74)90211-3. J Mol Biol. 1974. PMID: 4208607 No abstract available.

8

Separation of random fragments of DNA according to properties of their sequences.

Fischer SG, Lerman LS. Fischer SG, et al. Among authors: lerman ls. Proc Natl Acad Sci U S A. 1980 Aug;77(8):4420-4. doi: 10.1073/pnas.77.8.4420. Proc Natl Acad Sci U S A. 1980. PMID: 6254023 Free PMC article.

9

DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: correspondence with melting theory.

Fischer SG, Lerman LS. Fischer SG, et al. Among authors: lerman ls. Proc Natl Acad Sci U S A. 1983 Mar;80(6):1579-83. doi: 10.1073/pnas.80.6.1579. Proc Natl Acad Sci U S A. 1983. PMID: 6220406 Free PMC article.

10

Preferential isolation of DNA fragments associated with CpG islands.

Shiraishi M, Lerman LS, Sekiya T. Shiraishi M, et al. Among authors: lerman ls. Proc Natl Acad Sci U S A. 1995 May 9;92(10):4229-33. doi: 10.1073/pnas.92.10.4229. Proc Natl Acad Sci U S A. 1995. PMID: 7753787 Free PMC article.

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