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Gene expression profiling of patient-derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts.
Bian B, Bigonnet M, Gayet O, Loncle C, Maignan A, Gilabert M, Moutardier V, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Ouaissi M, Secq V, Poizat F, Nicolle R, Blum Y, Marisa L, Rubis M, Raoul JL, Bradner JE, Qi J, Lomberk G, Urrutia R, Saul A, Dusetti N, Iovanna J. Bian B, et al. Among authors: blum y. EMBO Mol Med. 2017 Apr;9(4):482-497. doi: 10.15252/emmm.201606975. EMBO Mol Med. 2017. PMID: 28275007 Free PMC article.
Pancreatic Adenocarcinoma Therapeutic Targets Revealed by Tumor-Stroma Cross-Talk Analyses in Patient-Derived Xenografts.
Nicolle R, Blum Y, Marisa L, Loncle C, Gayet O, Moutardier V, Turrini O, Giovannini M, Bian B, Bigonnet M, Rubis M, Elarouci N, Armenoult L, Ayadi M, Duconseil P, Gasmi M, Ouaissi M, Maignan A, Lomberk G, Boher JM, Ewald J, Bories E, Garnier J, Goncalves A, Poizat F, Raoul JL, Secq V, Garcia S, Grandval P, Barraud-Blanc M, Norguet E, Gilabert M, Delpero JR, Roques J, Calvo E, Guillaumond F, Vasseur S, Urrutia R, de Reyniès A, Dusetti N, Iovanna J. Nicolle R, et al. Among authors: blum y. Cell Rep. 2017 Nov 28;21(9):2458-2470. doi: 10.1016/j.celrep.2017.11.003. Cell Rep. 2017. PMID: 29186684 Free PMC article.
Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes.
Lomberk G, Blum Y, Nicolle R, Nair A, Gaonkar KS, Marisa L, Mathison A, Sun Z, Yan H, Elarouci N, Armenoult L, Ayadi M, Ordog T, Lee JH, Oliver G, Klee E, Moutardier V, Gayet O, Bian B, Duconseil P, Gilabert M, Bigonnet M, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Secq V, De Reyniès A, Dusetti N, Iovanna J, Urrutia R. Lomberk G, et al. Among authors: blum y. Nat Commun. 2018 May 17;9(1):1978. doi: 10.1038/s41467-018-04383-6. Nat Commun. 2018. PMID: 29773832 Free PMC article.
Stratification of Pancreatic Ductal Adenocarcinomas Based on Tumor and Microenvironment Features.
Puleo F, Nicolle R, Blum Y, Cros J, Marisa L, Demetter P, Quertinmont E, Svrcek M, Elarouci N, Iovanna J, Franchimont D, Verset L, Galdon MG, Devière J, de Reyniès A, Laurent-Puig P, Van Laethem JL, Bachet JB, Maréchal R. Puleo F, et al. Among authors: blum y. Gastroenterology. 2018 Dec;155(6):1999-2013.e3. doi: 10.1053/j.gastro.2018.08.033. Epub 2018 Aug 27. Gastroenterology. 2018. PMID: 30165049
Establishment of a pancreatic adenocarcinoma molecular gradient (PAMG) that predicts the clinical outcome of pancreatic cancer.
Nicolle R, Blum Y, Duconseil P, Vanbrugghe C, Brandone N, Poizat F, Roques J, Bigonnet M, Gayet O, Rubis M, Elarouci N, Armenoult L, Ayadi M, de Reyniès A, Giovannini M, Grandval P, Garcia S, Canivet C, Cros J, Bournet B, Buscail L; BACAP Consortium; Moutardier V, Gilabert M, Iovanna J, Dusetti N. Nicolle R, et al. Among authors: blum y. EBioMedicine. 2020 Jul;57:102858. doi: 10.1016/j.ebiom.2020.102858. Epub 2020 Jul 3. EBioMedicine. 2020. PMID: 32629389 Free PMC article.
Pancreatic Ductal Adenocarcinoma Arising in Young and Old Patients Displays Similar Molecular Features.
Raffenne J, Martin FA, Nicolle R, Konta M, Blum Y, Torrisani J, Puleo F, Bachet JB, Svrcek M, Bardier-Dupas A, Emile JF, Demetter P, Radman M, Van Laethem JL, Hammel P, Rebours V, Paradis V, Couvelard A, Cros J. Raffenne J, et al. Among authors: blum y. Cancers (Basel). 2021 Mar 11;13(6):1234. doi: 10.3390/cancers13061234. Cancers (Basel). 2021. PMID: 33799792 Free PMC article.
Intratumor CMS Heterogeneity Impacts Patient Prognosis in Localized Colon Cancer.
Marisa L, Blum Y, Taieb J, Ayadi M, Pilati C, Le Malicot K, Lepage C, Salazar R, Aust D, Duval A, Blons H, Taly V, Gentien D, Rapinat A, Selves J, Mouillet-Richard S, Boige V, Emile JF, de Reyniès A, Laurent-Puig P. Marisa L, et al. Among authors: blum y. Clin Cancer Res. 2021 Sep 1;27(17):4768-4780. doi: 10.1158/1078-0432.CCR-21-0529. Epub 2021 Jun 24. Clin Cancer Res. 2021. PMID: 34168047 Free PMC article.
DECONbench: a benchmarking platform dedicated to deconvolution methods for tumor heterogeneity quantification.
Decamps C, Arnaud A, Petitprez F, Ayadi M, Baurès A, Armenoult L; HADACA consortium; Escalera S, Guyon I, Nicolle R, Tomasini R, de Reyniès A, Cros J, Blum Y, Richard M. Decamps C, et al. Among authors: blum y. BMC Bioinformatics. 2021 Oct 2;22(1):473. doi: 10.1186/s12859-021-04381-4. BMC Bioinformatics. 2021. PMID: 34600479 Free PMC article.
82 results