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The circadian clock gene BMAL1 is a novel therapeutic target for malignant pleural mesothelioma.
Elshazley M, Sato M, Hase T, Yamashita R, Yoshida K, Toyokuni S, Ishiguro F, Osada H, Sekido Y, Yokoi K, Usami N, Shames DS, Kondo M, Gazdar AF, Minna JD, Hasegawa Y. Elshazley M, et al. Among authors: yoshida k. Int J Cancer. 2012 Dec 15;131(12):2820-31. doi: 10.1002/ijc.27598. Epub 2012 May 14. Int J Cancer. 2012. PMID: 22510946 Free PMC article.
Knockdown of ZEB1, a master epithelial-to-mesenchymal transition (EMT) gene, suppresses anchorage-independent cell growth of lung cancer cells.
Takeyama Y, Sato M, Horio M, Hase T, Yoshida K, Yokoyama T, Nakashima H, Hashimoto N, Sekido Y, Gazdar AF, Minna JD, Kondo M, Hasegawa Y. Takeyama Y, et al. Among authors: yoshida k. Cancer Lett. 2010 Oct 28;296(2):216-24. doi: 10.1016/j.canlet.2010.04.008. Epub 2010 May 7. Cancer Lett. 2010. PMID: 20452118 Free PMC article.
Pivotal role of epithelial cell adhesion molecule in the survival of lung cancer cells.
Hase T, Sato M, Yoshida K, Girard L, Takeyama Y, Horio M, Elshazley M, Oguri T, Sekido Y, Shames DS, Gazdar AF, Minna JD, Kondo M, Hasegawa Y. Hase T, et al. Among authors: yoshida k. Cancer Sci. 2011 Aug;102(8):1493-500. doi: 10.1111/j.1349-7006.2011.01973.x. Epub 2011 Jun 2. Cancer Sci. 2011. PMID: 21535318 Free PMC article.
Transient but not stable ZEB1 knockdown dramatically inhibits growth of malignant pleural mesothelioma cells.
Horio M, Sato M, Takeyama Y, Elshazley M, Yamashita R, Hase T, Yoshida K, Usami N, Yokoi K, Sekido Y, Kondo M, Toyokuni S, Gazdar AF, Minna JD, Hasegawa Y. Horio M, et al. Among authors: yoshida k. Ann Surg Oncol. 2012 Jul;19 Suppl 3(Suppl 3):S634-45. doi: 10.1245/s10434-011-2142-0. Epub 2011 Nov 16. Ann Surg Oncol. 2012. PMID: 22086445 Free PMC article.
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