Ohta K - Search Results

1

Novel androgen receptor full antagonists: Design, synthesis, and a docking study of glycerol and aminoglycerol derivatives that contain p-carborane cages.

Kaise A, Ohta K, Fujii S, Oda A, Goto T, Endo Y. Kaise A, et al. Among authors: ohta k. Bioorg Med Chem. 2018 Jul 30;26(13):3805-3811. doi: 10.1016/j.bmc.2018.06.007. Epub 2018 Jun 7. Bioorg Med Chem. 2018. PMID: 29903411

2

Novel retinoid X receptor (RXR) antagonists having a dicarba-closo-dodecaborane as a hydrophobic moiety.

Ohta K, Iijima T, Kawachi E, Kagechika H, Endo Y. Ohta K, et al. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5913-8. doi: 10.1016/j.bmcl.2004.09.035. Bioorg Med Chem Lett. 2004. PMID: 15501068

3

Potent estrogen receptor ligands based on bisphenols with a globular hydrophobic core.

Endo Y, Yoshimi T, Ohta K, Suzuki T, Ohta S. Endo Y, et al. Among authors: ohta s, ohta k. J Med Chem. 2005 Jun 16;48(12):3941-4. doi: 10.1021/jm050195r. J Med Chem. 2005. PMID: 15943468

4

Potent androgen antagonists based on carborane as a hydrophobic core structure.

Fujii S, Goto T, Ohta K, Hashimoto Y, Suzuki T, Ohta S, Endo Y. Fujii S, et al. Among authors: ohta s, ohta k. J Med Chem. 2005 Jul 14;48(14):4654-62. doi: 10.1021/jm050115j. J Med Chem. 2005. PMID: 16000001

5

Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes.

Goto T, Ohta K, Suzuki T, Ohta S, Endo Y. Goto T, et al. Among authors: ohta s, ohta k. Bioorg Med Chem. 2005 Dec 1;13(23):6414-24. doi: 10.1016/j.bmc.2005.06.061. Epub 2005 Aug 15. Bioorg Med Chem. 2005. PMID: 16099660

6

m-Carborane bisphenol structure as a pharmacophore for selective estrogen receptor modulators.

Ogawa T, Ohta K, Yoshimi T, Yamazaki H, Suzuki T, Ohta S, Endo Y. Ogawa T, et al. Among authors: ohta s, ohta k. Bioorg Med Chem Lett. 2006 Aug 1;16(15):3943-6. doi: 10.1016/j.bmcl.2006.05.032. Epub 2006 Jun 2. Bioorg Med Chem Lett. 2006. PMID: 16735120

7

Design and synthesis of carborane-containing androgen receptor (AR) antagonist bearing a pyridine ring.

Ohta K, Goto T, Fijii S, Suzuki T, Ohta S, Endo Y. Ohta K, et al. Among authors: ohta s. Bioorg Med Chem. 2008 Sep 1;16(17):8022-8. doi: 10.1016/j.bmc.2008.07.055. Epub 2008 Jul 24. Bioorg Med Chem. 2008. PMID: 18707892

8

Promising core structure for nuclear receptor ligands: design and synthesis of novel estrogen receptor ligands based on diphenylamine skeleton.

Ohta K, Chiba Y, Ogawa T, Endo Y. Ohta K, et al. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5050-3. doi: 10.1016/j.bmcl.2008.08.004. Epub 2008 Aug 6. Bioorg Med Chem Lett. 2008. PMID: 18760603

9

Acidic heterocycles as novel hydrophilic pharmacophore of androgen receptor ligands with a carborane core structure.

Fujii S, Ohta K, Goto T, Kagechika H, Endo Y. Fujii S, et al. Among authors: ohta k. Bioorg Med Chem. 2009 Jan 1;17(1):344-50. doi: 10.1016/j.bmc.2008.10.060. Epub 2008 Oct 30. Bioorg Med Chem. 2009. PMID: 19022677

10

Synthesis and biological evaluation of p-carborane bisphenols and their derivatives: structure-activity relationship for estrogenic activity.

Ogawa T, Ohta K, Iijima T, Suzuki T, Ohta S, Endo Y. Ogawa T, et al. Among authors: ohta s, ohta k. Bioorg Med Chem. 2009 Feb 1;17(3):1109-17. doi: 10.1016/j.bmc.2008.12.044. Epub 2008 Dec 25. Bioorg Med Chem. 2009. PMID: 19141368

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