Chen L - Search Results

1

Diet Modifies Colonic Microbiota and CD4⁺ T-Cell Repertoire to Induce Flares of Colitis in Mice With Myeloid-Cell Expression of Interleukin 23.

Chen L, He Z, Iuga AC, Martins Filho SN, Faith JJ, Clemente JC, Deshpande M, Jayaprakash A, Colombel JF, Lafaille JJ, Sachidanandam R, Furtado GC, Lira SA. Chen L, et al. Gastroenterology. 2018 Oct;155(4):1177-1191.e16. doi: 10.1053/j.gastro.2018.06.034. Epub 2018 Jun 15. Gastroenterology. 2018. PMID: 29909020 Free PMC article.

2

Food colorants metabolized by commensal bacteria promote colitis in mice with dysregulated expression of interleukin-23.

He Z, Chen L, Catalan-Dibene J, Bongers G, Faith JJ, Suebsuwong C, DeVita RJ, Shen Z, Fox JG, Lafaille JJ, Furtado GC, Lira SA. He Z, et al. Among authors: chen l. Cell Metab. 2021 Jul 6;33(7):1358-1371.e5. doi: 10.1016/j.cmet.2021.04.015. Epub 2021 May 13. Cell Metab. 2021. PMID: 33989521 Free PMC article.

3

Interleukin 33 regulates gene expression in intestinal epithelial cells independently of its nuclear localization.

He Z, Chen L, Furtado GC, Lira SA. He Z, et al. Among authors: chen l. Cytokine. 2018 Nov;111:146-153. doi: 10.1016/j.cyto.2018.08.009. Epub 2018 Aug 23. Cytokine. 2018. PMID: 30145369 Free PMC article.

4

Interleukin 1 beta and Matrix Metallopeptidase 3 Contribute to Development of Epidermal Growth Factor Receptor-Dependent Serrated Polyps in Mouse Cecum.

He Z, Chen L, Chen G, Smaldini P, Bongers G, Catalan-Dibene J, Furtado GC, Lira SA. He Z, et al. Among authors: chen l, chen g. Gastroenterology. 2019 Dec;157(6):1572-1583.e8. doi: 10.1053/j.gastro.2019.08.025. Epub 2019 Aug 27. Gastroenterology. 2019. PMID: 31470007 Free PMC article.

5

Skin expression of IL-23 drives the development of psoriasis and psoriatic arthritis in mice.

Chen L, Deshpande M, Grisotto M, Smaldini P, Garcia R, He Z, Gulko PS, Lira SA, Furtado GC. Chen L, et al. Sci Rep. 2020 May 19;10(1):8259. doi: 10.1038/s41598-020-65269-6. Sci Rep. 2020. PMID: 32427877 Free PMC article.

6

IFN-γ⁺ cytotoxic CD4⁺ T lymphocytes are involved in the pathogenesis of colitis induced by IL-23 and the food colorant Red 40.

Chen L, He Z, Reis BS, Gelles JD, Chipuk JE, Ting AT, Spicer JA, Trapani JA, Furtado GC, Lira SA. Chen L, et al. Cell Mol Immunol. 2022 Jul;19(7):777-790. doi: 10.1038/s41423-022-00864-3. Epub 2022 Apr 25. Cell Mol Immunol. 2022. PMID: 35468944 Free PMC article.

7

Interplay of host microbiota, genetic perturbations, and inflammation promotes local development of intestinal neoplasms in mice.

Bongers G, Pacer ME, Geraldino TH, Chen L, He Z, Hashimoto D, Furtado GC, Ochando J, Kelley KA, Clemente JC, Merad M, van Bakel H, Lira SA. Bongers G, et al. Among authors: chen l. J Exp Med. 2014 Mar 10;211(3):457-72. doi: 10.1084/jem.20131587. Epub 2014 Mar 3. J Exp Med. 2014. PMID: 24590763 Free PMC article.

8

Epithelial-derived IL-33 promotes intestinal tumorigenesis in Apc ^Min/+ mice.

He Z, Chen L, Souto FO, Canasto-Chibuque C, Bongers G, Deshpande M, Harpaz N, Ko HM, Kelley K, Furtado GC, Lira SA. He Z, et al. Among authors: chen l. Sci Rep. 2017 Jul 14;7(1):5520. doi: 10.1038/s41598-017-05716-z. Sci Rep. 2017. PMID: 28710436 Free PMC article.

9

Interleukin 22 disrupts pancreatic function in newborn mice expressing IL-23.

Chen L, Strohmeier V, He Z, Deshpande M, Catalan-Dibene J, Durum SK, Moran TM, Kraus T, Xiong H, Faith JJ, Sodhi CP, Hackam DJ, Lira SA, Furtado GC. Chen L, et al. Nat Commun. 2019 Oct 4;10(1):4517. doi: 10.1038/s41467-019-12540-8. Nat Commun. 2019. PMID: 31586069 Free PMC article.

10

IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology.

Chen L, He Z, Slinger E, Bongers G, Lapenda TLS, Pacer ME, Jiao J, Beltrao MF, Soto AJ, Harpaz N, Gordon RE, Ochando JC, Oukka M, Iuga AC, Chensue SW, Blander JM, Furtado GC, Lira SA. Chen L, et al. Mucosal Immunol. 2015 Mar;8(2):390-402. doi: 10.1038/mi.2014.77. Epub 2014 Aug 27. Mucosal Immunol. 2015. PMID: 25160819 Free PMC article.

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