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Page 1
Tuning the Diels-Alder Reaction for Bioconjugation to Maleimide Drug-Linkers.
St Amant AH, Lemen D, Florinas S, Mao S, Fazenbaker C, Zhong H, Wu H, Gao C, Christie RJ, Read de Alaniz J. St Amant AH, et al. Among authors: lemen d. Bioconjug Chem. 2018 Jul 18;29(7):2406-2414. doi: 10.1021/acs.bioconjchem.8b00320. Epub 2018 Jun 22. Bioconjug Chem. 2018. PMID: 29932647
A Diene-Containing Noncanonical Amino Acid Enables Dual Functionality in Proteins: Rapid Diels-Alder Reaction with Maleimide or Proximity-Based Dimerization.
St Amant AH, Huang F, Lin J, Rickert K, Oganesyan V, Lemen D, Mao S, Harper J, Marelli M, Wu H, Gao C, Read de Alaniz J, Christie RJ. St Amant AH, et al. Among authors: lemen d. Angew Chem Int Ed Engl. 2019 Jun 17;58(25):8489-8493. doi: 10.1002/anie.201903494. Epub 2019 May 14. Angew Chem Int Ed Engl. 2019. PMID: 31018033 Free PMC article.
A Reactive Antibody Platform for One-Step Production of Antibody-Drug Conjugates through a Diels-Alder Reaction with Maleimide.
St Amant AH, Huang F, Lin J, Lemen D, Chakiath C, Mao S, Fazenbaker C, Zhong H, Harper J, Xu W, Patel N, Adams L, Vijayakrishnan B, Howard PW, Marelli M, Wu H, Gao C, Read de Alaniz J, Christie RJ. St Amant AH, et al. Among authors: lemen d. Bioconjug Chem. 2019 Sep 18;30(9):2340-2348. doi: 10.1021/acs.bioconjchem.9b00436. Epub 2019 Aug 19. Bioconjug Chem. 2019. PMID: 31380623
Associations of Circulating ANGPTL3, C-Terminal Domain-Containing ANGPTL4, and ANGPTL3/8 and ANGPTL4/8 Complexes with LPL Activity, Diabetes, Inflammation, and Cardiovascular Mortality.
Silbernagel G, Chen YQ, Li H, Lemen D, Wen Y, Zhen EY, Rief M, Kleber ME, Delgado G, Sarzynski MA, Qian YW, Schmidt B, Erbel R, Trampisch U, Moissl AP, Rudolf H, Schunkert H, Stang A, März W, Trampisch HJ, Scharnagl H, Konrad RJ. Silbernagel G, et al. Among authors: lemen d. Circulation. 2024 Oct 11. doi: 10.1161/CIRCULATIONAHA.124.069272. Online ahead of print. Circulation. 2024. PMID: 39392008