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Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation.
Held NM, Kuipers EN, van Weeghel M, van Klinken JB, Denis SW, Lombès M, Wanders RJ, Vaz FM, Rensen PCN, Verhoeven AJ, Boon MR, Houtkooper RH. Held NM, et al. Among authors: van weeghel m, van klinken jb. Sci Rep. 2018 Jun 22;8(1):9562. doi: 10.1038/s41598-018-27875-3. Sci Rep. 2018. PMID: 29934543 Free PMC article.
Muscle abnormalities worsen after post-exertional malaise in long COVID.
Appelman B, Charlton BT, Goulding RP, Kerkhoff TJ, Breedveld EA, Noort W, Offringa C, Bloemers FW, van Weeghel M, Schomakers BV, Coelho P, Posthuma JJ, Aronica E, Joost Wiersinga W, van Vugt M, Wüst RCI. Appelman B, et al. Among authors: van weeghel m, van vugt m. Nat Commun. 2024 Jan 4;15(1):17. doi: 10.1038/s41467-023-44432-3. Nat Commun. 2024. PMID: 38177128 Free PMC article.
Mitochondrial long chain fatty acid beta-oxidation in man and mouse.
Chegary M, Brinke Ht, Ruiter JP, Wijburg FA, Stoll MS, Minkler PE, van Weeghel M, Schulz H, Hoppel CL, Wanders RJ, Houten SM. Chegary M, et al. Among authors: van weeghel m. Biochim Biophys Acta. 2009 Aug;1791(8):806-15. doi: 10.1016/j.bbalip.2009.05.006. Epub 2009 May 22. Biochim Biophys Acta. 2009. PMID: 19465148 Free PMC article.
Fasting-induced myocardial lipid accumulation in long-chain acyl-CoA dehydrogenase knockout mice is accompanied by impaired left ventricular function.
Bakermans AJ, Geraedts TR, van Weeghel M, Denis S, João Ferraz M, Aerts JM, Aten J, Nicolay K, Houten SM, Prompers JJ. Bakermans AJ, et al. Among authors: van weeghel m. Circ Cardiovasc Imaging. 2011 Sep;4(5):558-65. doi: 10.1161/CIRCIMAGING.111.963751. Epub 2011 Jul 7. Circ Cardiovasc Imaging. 2011. PMID: 21737602
Food withdrawal lowers energy expenditure and induces inactivity in long-chain fatty acid oxidation-deficient mouse models.
Diekman EF, van Weeghel M, Wanders RJ, Visser G, Houten SM. Diekman EF, et al. Among authors: van weeghel m. FASEB J. 2014 Jul;28(7):2891-900. doi: 10.1096/fj.14-250241. Epub 2014 Mar 19. FASEB J. 2014. PMID: 24648546
We suggest that mice are partly protected against the negative consequence of an FAO defect.-Diekman, E. F., van Weeghel, M., Wanders, R. J. A., Visser, G., Houten, S. M. Food withdrawal lowers energy expenditure and induces inactivity in long-chain fa …
We suggest that mice are partly protected against the negative consequence of an FAO defect.-Diekman, E. F., van Weeghel, M …
Increased cardiac fatty acid oxidation in a mouse model with decreased malonyl-CoA sensitivity of CPT1B.
van Weeghel M, Abdurrachim D, Nederlof R, Argmann CA, Houtkooper RH, Hagen J, Nabben M, Denis S, Ciapaite J, Kolwicz SC Jr, Lopaschuk GD, Auwerx J, Nicolay K, Des Rosiers C, Wanders RJ, Zuurbier CJ, Prompers JJ, Houten SM. van Weeghel M, et al. Cardiovasc Res. 2018 Aug 1;114(10):1324-1334. doi: 10.1093/cvr/cvy089. Cardiovasc Res. 2018. PMID: 29635338
Barth syndrome cells display widespread remodeling of mitochondrial complexes without affecting metabolic flux distribution.
Chatzispyrou IA, Guerrero-Castillo S, Held NM, Ruiter JPN, Denis SW, IJlst L, Wanders RJ, van Weeghel M, Ferdinandusse S, Vaz FM, Brandt U, Houtkooper RH. Chatzispyrou IA, et al. Among authors: van weeghel m. Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3650-3658. doi: 10.1016/j.bbadis.2018.08.041. Epub 2018 Sep 1. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 30251684 Free article.
100 results