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240 results

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Page 1
Identifying and targeting ROS1 gene fusions in non-small cell lung cancer.
Davies KD, Le AT, Theodoro MF, Skokan MC, Aisner DL, Berge EM, Terracciano LM, Cappuzzo F, Incarbone M, Roncalli M, Alloisio M, Santoro A, Camidge DR, Varella-Garcia M, Doebele RC. Davies KD, et al. Among authors: le at. Clin Cancer Res. 2012 Sep 1;18(17):4570-9. doi: 10.1158/1078-0432.CCR-12-0550. Epub 2012 Aug 23. Clin Cancer Res. 2012. PMID: 22919003 Free PMC article.
Oncogenic fusions involving exon 19 of ALK.
Le AT, Varella-Garcia M, Doebele RC. Le AT, et al. J Thorac Oncol. 2012 Dec;7(12):e44. doi: 10.1097/JTO.0b013e31826bb94d. J Thorac Oncol. 2012. PMID: 23154568 Free PMC article. No abstract available.
Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer.
Vaishnavi A, Capelletti M, Le AT, Kako S, Butaney M, Ercan D, Mahale S, Davies KD, Aisner DL, Pilling AB, Berge EM, Kim J, Sasaki H, Park S, Kryukov G, Garraway LA, Hammerman PS, Haas J, Andrews SW, Lipson D, Stephens PJ, Miller VA, Varella-Garcia M, Jänne PA, Doebele RC. Vaishnavi A, et al. Among authors: le at. Nat Med. 2013 Nov;19(11):1469-1472. doi: 10.1038/nm.3352. Epub 2013 Oct 27. Nat Med. 2013. PMID: 24162815 Free PMC article.
ROS1 and ALK fusions in colorectal cancer, with evidence of intratumoral heterogeneity for molecular drivers.
Aisner DL, Nguyen TT, Paskulin DD, Le AT, Haney J, Schulte N, Chionh F, Hardingham J, Mariadason J, Tebbutt N, Doebele RC, Weickhardt AJ, Varella-Garcia M. Aisner DL, et al. Among authors: le at. Mol Cancer Res. 2014 Jan;12(1):111-8. doi: 10.1158/1541-7786.MCR-13-0479-T. Epub 2013 Dec 2. Mol Cancer Res. 2014. PMID: 24296758 Free PMC article. Clinical Trial.
The democratization of the oncogene.
Le AT, Doebele RC. Le AT, et al. Cancer Discov. 2014 Aug;4(8):870-2. doi: 10.1158/2159-8290.CD-14-0628. Cancer Discov. 2014. PMID: 25092743 Free PMC article.
TRKing down an old oncogene in a new era of targeted therapy.
Vaishnavi A, Le AT, Doebele RC. Vaishnavi A, et al. Among authors: le at. Cancer Discov. 2015 Jan;5(1):25-34. doi: 10.1158/2159-8290.CD-14-0765. Epub 2014 Dec 19. Cancer Discov. 2015. PMID: 25527197 Free PMC article. Review.
An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101.
Doebele RC, Davis LE, Vaishnavi A, Le AT, Estrada-Bernal A, Keysar S, Jimeno A, Varella-Garcia M, Aisner DL, Li Y, Stephens PJ, Morosini D, Tuch BB, Fernandes M, Nanda N, Low JA. Doebele RC, et al. Among authors: le at. Cancer Discov. 2015 Oct;5(10):1049-57. doi: 10.1158/2159-8290.CD-15-0443. Epub 2015 Jul 27. Cancer Discov. 2015. PMID: 26216294 Free PMC article. Clinical Trial.
240 results