Ding HW - Search Results

1

Design, synthesis and biological evaluation of novel series of 2H-benzo[b][1,4]oxazin-3(4H)-one and 2H-benzo[b][1,4]oxazine scaffold derivatives as PI3Kα inhibitors.

Dong FD, Liu DD, Deng CL, Qin XC, Chen K, Wang J, Song HR, Ding HW. Dong FD, et al. Among authors: ding hw. Bioorg Med Chem. 2018 Aug 7;26(14):3982-3991. doi: 10.1016/j.bmc.2018.06.022. Epub 2018 Jun 18. Bioorg Med Chem. 2018. PMID: 29937355

2

Synthesis and cytotoxic activity of some novel N-pyridinyl-2-(6-phenylimidazo[2,1-b]thiazol-3-yl)acetamide derivatives.

Ding H, Chen Z, Zhang C, Xin T, Wang Y, Song H, Jiang Y, Chen Y, Xu Y, Tan C. Ding H, et al. Molecules. 2012 Apr 23;17(4):4703-16. doi: 10.3390/molecules17044703. Molecules. 2012. PMID: 22525437 Free PMC article.

3

Design, synthesis, and biological evaluation of novel 3-substituted imidazo[1,2-a]pyridine and quinazolin-4(3H)-one derivatives as PI3Kα inhibitors.

Fan YH, Li W, Liu DD, Bai MX, Song HR, Xu YN, Lee S, Zhou ZP, Wang J, Ding HW. Fan YH, et al. Among authors: ding hw. Eur J Med Chem. 2017 Oct 20;139:95-106. doi: 10.1016/j.ejmech.2017.07.074. Epub 2017 Aug 1. Eur J Med Chem. 2017. PMID: 28800461

4

Synthesis and Smo Activity of Some Novel Benzamide Derivatives.

Ding H, Chen K, Song B, Deng C, Li W, Niu L, Bai M, Song H, Zhang L. Ding H, et al. Molecules. 2017 Dec 31;23(1):85. doi: 10.3390/molecules23010085. Molecules. 2017. PMID: 29301237 Free PMC article.

5

Design, synthesis and biological evaluation of novel 4-aminoquinazolines as dual target inhibitors of EGFR-PI3Kα.

Ding HW, Deng CL, Li DD, Liu DD, Chai SM, Wang W, Zhang Y, Chen K, Li X, Wang J, Song SJ, Song HR. Ding HW, et al. Eur J Med Chem. 2018 Feb 25;146:460-470. doi: 10.1016/j.ejmech.2018.01.081. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29407971

6

Novel 4-aminoquinazoline derivatives induce growth inhibition, cell cycle arrest and apoptosis via PI3Kα inhibition.

Fan YH, Ding HW, Liu DD, Song HR, Xu YN, Wang J. Fan YH, et al. Among authors: ding hw. Bioorg Med Chem. 2018 May 1;26(8):1675-1685. doi: 10.1016/j.bmc.2018.02.015. Epub 2018 Feb 13. Bioorg Med Chem. 2018. PMID: 29475582

7

A novel inhibitor of ADAM17 sensitizes colorectal cancer cells to 5-Fluorouracil by reversing Notch and epithelial-mesenchymal transition in vitro and in vivo.

Li DD, Zhao CH, Ding HW, Wu Q, Ren TS, Wang J, Chen CQ, Zhao QC. Li DD, et al. Among authors: ding hw. Cell Prolif. 2018 Oct;51(5):e12480. doi: 10.1111/cpr.12480. Epub 2018 Aug 2. Cell Prolif. 2018. PMID: 30069943 Free PMC article.

8

Daurinoline suppressed the migration and invasion of chemo-resistant human non-small cell lung cancer cells by reversing EMT and Notch-1 and sensitized the cells to Taxol.

Li DD, Qin XC, Yang Y, Chu HX, Li RL, Ma LX, Ding HW, Zhao QC. Li DD, et al. Among authors: ding hw. Environ Toxicol Pharmacol. 2019 Feb;66:109-115. doi: 10.1016/j.etap.2018.12.005. Epub 2018 Dec 6. Environ Toxicol Pharmacol. 2019. PMID: 30641414

9

Design, synthesis, and biological evaluation of some novel 4-aminoquinazolines as Pan-PI3K inhibitors.

Ding HW, Wang S, Qin XC, Wang J, Song HR, Zhao QC, Song SJ. Ding HW, et al. Bioorg Med Chem. 2019 Jul 1;27(13):2729-2740. doi: 10.1016/j.bmc.2019.04.024. Epub 2019 Apr 17. Bioorg Med Chem. 2019. PMID: 31097403

10

Design, synthesis and evaluation of some 1,6-disubstituted-1H-benzo[d]imidazoles derivatives targeted PI3K as anticancer agents.

Ding HW, Yu L, Bai MX, Qin XC, Song MT, Zhao QC. Ding HW, et al. Bioorg Chem. 2019 Dec;93:103283. doi: 10.1016/j.bioorg.2019.103283. Epub 2019 Sep 14. Bioorg Chem. 2019. PMID: 31585260

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