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Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.
Kirkman LA, Zhan W, Visone J, Dziedziech A, Singh PK, Fan H, Tong X, Bruzual I, Hara R, Kawasaki M, Imaeda T, Okamoto R, Sato K, Michino M, Alvaro EF, Guiang LF, Sanz L, Mota DJ, Govindasamy K, Wang R, Ling Y, Tumwebaze PK, Sukenick G, Shi L, Vendome J, Bhanot P, Rosenthal PJ, Aso K, Foley MA, Cooper RA, Kafsack B, Doggett JS, Nathan CF, Lin G. Kirkman LA, et al. Among authors: bhanot p. Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6863-E6870. doi: 10.1073/pnas.1806109115. Epub 2018 Jul 2. Proc Natl Acad Sci U S A. 2018. PMID: 29967165 Free PMC article.
Improved Plasmodium berghei lines for conditional mutagenesis.
Panchal D, Govindasamy K, Rana A, Bhanot P. Panchal D, et al. Among authors: bhanot p. Mol Biochem Parasitol. 2012 Jul;184(1):52-4. doi: 10.1016/j.molbiopara.2012.03.005. Epub 2012 Mar 23. Mol Biochem Parasitol. 2012. PMID: 22450301
84 results