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Proapoptotic modification of substituted isoindolinones as MDM2-p53 inhibitors.
Grigoreva TA, Novikova DS, Petukhov AV, Gureev MA, Garabadzhiu AV, Melino G, Barlev NA, Tribulovich VG. Grigoreva TA, et al. Among authors: petukhov av. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5197-5202. doi: 10.1016/j.bmcl.2017.10.049. Epub 2017 Oct 20. Bioorg Med Chem Lett. 2017. PMID: 29089230
Novel isatin-derived molecules activate p53 via interference with Mdm2 to promote apoptosis.
Fedorova O, Daks A, Petrova V, Petukhov A, Lezina L, Shuvalov O, Davidovich P, Kriger D, Lomert E, Tentler D, Kartsev V, Uyanik B, Tribulovich V, Demidov O, Melino G, Barlev NA. Fedorova O, et al. Among authors: petukhov a. Cell Cycle. 2018;17(15):1917-1930. doi: 10.1080/15384101.2018.1506664. Epub 2018 Sep 5. Cell Cycle. 2018. PMID: 30109812 Free PMC article.
The biological basis and clinical symptoms of CAR-T therapy-associated toxicites.
Titov A, Petukhov A, Staliarova A, Motorin D, Bulatov E, Shuvalov O, Soond SM, Piacentini M, Melino G, Zaritskey A, Barlev NA. Titov A, et al. Among authors: petukhov a. Cell Death Dis. 2018 Sep 4;9(9):897. doi: 10.1038/s41419-018-0918-x. Cell Death Dis. 2018. PMID: 30181581 Free PMC article. Review.
292 results