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SLC25A23 augments mitochondrial Ca²⁺ uptake, interacts with MCU, and induces oxidative stress-mediated cell death.
Hoffman NE, Chandramoorthy HC, Shanmughapriya S, Zhang XQ, Vallem S, Doonan PJ, Malliankaraman K, Guo S, Rajan S, Elrod JW, Koch WJ, Cheung JY, Madesh M. Hoffman NE, et al. Among authors: shanmughapriya s. Mol Biol Cell. 2014 Mar;25(6):936-47. doi: 10.1091/mbc.E13-08-0502. Epub 2014 Jan 15. Mol Biol Cell. 2014. PMID: 24430870 Free PMC article.
TRPM2 channels protect against cardiac ischemia-reperfusion injury: role of mitochondria.
Miller BA, Hoffman NE, Merali S, Zhang XQ, Wang J, Rajan S, Shanmughapriya S, Gao E, Barrero CA, Mallilankaraman K, Song J, Gu T, Hirschler-Laszkiewicz I, Koch WJ, Feldman AM, Madesh M, Cheung JY. Miller BA, et al. Among authors: shanmughapriya s. J Biol Chem. 2014 Mar 14;289(11):7615-29. doi: 10.1074/jbc.M113.533851. Epub 2014 Feb 3. J Biol Chem. 2014. PMID: 24492610 Free PMC article.
LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation.
Doonan PJ, Chandramoorthy HC, Hoffman NE, Zhang X, Cárdenas C, Shanmughapriya S, Rajan S, Vallem S, Chen X, Foskett JK, Cheung JY, Houser SR, Madesh M. Doonan PJ, et al. Among authors: shanmughapriya s. FASEB J. 2014 Nov;28(11):4936-49. doi: 10.1096/fj.14-256453. Epub 2014 Jul 30. FASEB J. 2014. PMID: 25077561 Free PMC article.
A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α.
Chen SJ, Hoffman NE, Shanmughapriya S, Bao L, Keefer K, Conrad K, Merali S, Takahashi Y, Abraham T, Hirschler-Laszkiewicz I, Wang J, Zhang XQ, Song J, Barrero C, Shi Y, Kawasawa YI, Bayerl M, Sun T, Barbour M, Wang HG, Madesh M, Cheung JY, Miller BA. Chen SJ, et al. Among authors: shanmughapriya s. J Biol Chem. 2014 Dec 26;289(52):36284-302. doi: 10.1074/jbc.M114.620922. Epub 2014 Nov 12. J Biol Chem. 2014. PMID: 25391657 Free PMC article.
Ca²⁺ entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance.
Hoffman NE, Miller BA, Wang J, Elrod JW, Rajan S, Gao E, Song J, Zhang XQ, Hirschler-Laszkiewicz I, Shanmughapriya S, Koch WJ, Feldman AM, Madesh M, Cheung JY. Hoffman NE, et al. Among authors: shanmughapriya s. Am J Physiol Heart Circ Physiol. 2015 Mar 15;308(6):H637-50. doi: 10.1152/ajpheart.00720.2014. Epub 2015 Jan 9. Am J Physiol Heart Circ Physiol. 2015. PMID: 25576627 Free PMC article.
The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition.
Luongo TS, Lambert JP, Yuan A, Zhang X, Gross P, Song J, Shanmughapriya S, Gao E, Jain M, Houser SR, Koch WJ, Cheung JY, Madesh M, Elrod JW. Luongo TS, et al. Among authors: shanmughapriya s. Cell Rep. 2015 Jul 7;12(1):23-34. doi: 10.1016/j.celrep.2015.06.017. Epub 2015 Jun 25. Cell Rep. 2015. PMID: 26119731 Free PMC article.
SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore.
Shanmughapriya S, Rajan S, Hoffman NE, Higgins AM, Tomar D, Nemani N, Hines KJ, Smith DJ, Eguchi A, Vallem S, Shaikh F, Cheung M, Leonard NJ, Stolakis RS, Wolfers MP, Ibetti J, Chuprun JK, Jog NR, Houser SR, Koch WJ, Elrod JW, Madesh M. Shanmughapriya S, et al. Mol Cell. 2015 Oct 1;60(1):47-62. doi: 10.1016/j.molcel.2015.08.009. Epub 2015 Sep 17. Mol Cell. 2015. PMID: 26387735 Free PMC article.
71 results