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Immune reprogramming via PD-1 inhibition enhances early-stage lung cancer survival.
Markowitz GJ, Havel LS, Crowley MJ, Ban Y, Lee SB, Thalappillil JS, Narula N, Bhinder B, Elemento O, Wong ST, Gao D, Altorki NK, Mittal V. Markowitz GJ, et al. Among authors: crowley mj. JCI Insight. 2018 Jul 12;3(13):e96836. doi: 10.1172/jci.insight.96836. JCI Insight. 2018. PMID: 29997286 Free PMC article.
Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis.
Poulos MG, Ramalingam P, Gutkin MC, Kleppe M, Ginsberg M, Crowley MJP, Elemento O, Levine RL, Rafii S, Kitajewski J, Greenblatt MB, Shim JH, Butler JM. Poulos MG, et al. Nat Commun. 2016 Dec 21;7:13829. doi: 10.1038/ncomms13829. Nat Commun. 2016. PMID: 28000664 Free PMC article.
Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis.
Lourenco AR, Ban Y, Crowley MJ, Lee SB, Ramchandani D, Du W, Elemento O, George JT, Jolly MK, Levine H, Sheng J, Wong ST, Altorki NK, Gao D. Lourenco AR, et al. Among authors: crowley mj. Cancer Res. 2020 Jan 15;80(2):163-169. doi: 10.1158/0008-5472.CAN-19-1427. Epub 2019 Nov 8. Cancer Res. 2020. PMID: 31704888 Free PMC article.
Tumor-intrinsic IRE1α signaling controls protective immunity in lung cancer.
Crowley MJP, Bhinder B, Markowitz GJ, Martin M, Verma A, Sandoval TA, Chae CS, Yomtoubian S, Hu Y, Chopra S, Tavarez DA, Giovanelli P, Gao D, McGraw TE, Altorki NK, Elemento O, Cubillos-Ruiz JR, Mittal V. Crowley MJP, et al. Nat Commun. 2023 Jan 9;14(1):120. doi: 10.1038/s41467-022-35584-9. Nat Commun. 2023. PMID: 36624093 Free PMC article.
Deficiency of metabolic regulator PKM2 activates the pentose phosphate pathway and generates TCF1+ progenitor CD8+ T cells to improve checkpoint blockade.
Markowitz GJ, Ban Y, Tavarez DA, Yoffe L, Podaza E, He Y, Martin MT, Crowley MJP, Sandoval TA, Gao D, Martin ML, Elemento O, Cubillos-Ruiz JR, McGraw TE, Altorki NK, Mittal V. Markowitz GJ, et al. Res Sq [Preprint]. 2023 Sep 21:rs.3.rs-3356477. doi: 10.21203/rs.3.rs-3356477/v1. Res Sq. 2023. Update in: Nat Immunol. 2024 Oct;25(10):1884-1899. doi: 10.1038/s41590-024-01963-1 PMID: 37790365 Free PMC article. Updated. Preprint.
268 results