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Act1 is a negative regulator in T and B cells via direct inhibition of STAT3.
Zhang CJ, Wang C, Jiang M, Gu C, Xiao J, Chen X, Martin BN, Tang F, Yamamoto E, Xian Y, Wang H, Li F, Sartor RB, Smith H, Husni ME, Shi FD, Gao J, Carman J, Dongre A, McKarns SC, Coppieters K, Jørgensen TN, Leonard WJ, Li X. Zhang CJ, et al. Among authors: husni me. Nat Commun. 2018 Jul 16;9(1):2745. doi: 10.1038/s41467-018-04974-3. Nat Commun. 2018. PMID: 30013031 Free PMC article.
Management of Concomitant Inflammatory Bowel Disease or Uveitis in Patients with Psoriatic Arthritis: An Updated Review Informing the 2021 GRAPPA Treatment Recommendations.
Jadon DR, Corp N, van der Windt DA, Coates LC, Soriano ER, Kavanaugh A, Raine T, Rieder F, Siebert S, Zummer M, Schwartzman S, Rosenbaum JT, Michelsen B, Laxminarayan R, Wu D, Gupta L, Ng B, Jethwa H, De Windt N, Gudu T, Hutton J, O'Sullivan D, Luchetti MM, Stoll M, Singh JA, Peluso R, Rademacher J, Husni ME. Jadon DR, et al. Among authors: husni me. J Rheumatol. 2023 Mar;50(3):438-450. doi: 10.3899/jrheum.220317. Epub 2022 Dec 1. J Rheumatol. 2023. PMID: 36455946 Free PMC article. Review.
Proceedings of the GRAPPA 2022 Executive Retreat.
Ng BCK, Jadon D, Adebajo A, Ayan G, Duffin KC, Chandran V, Coates LC, D'Agostino MA, de Vlam K, Deodhar A, Eder L, Garg A, Gladman DD, Goel N, Gottlieb AB, Husni ME, Katz A, Kavanaugh A, Lubrano E, Mease PJ, Merola JF, Nash P, Ogdie A, Pennington SR, Perez-Chada LM, Proft F, Rosen CF, Savage L, Goldenstein-Schainberg C, Siebert S, Soriano ER, Steinkoenig I, Tillett W, Armstrong AW, FitzGerald O. Ng BCK, et al. Among authors: husni me. J Rheumatol. 2023 Nov;50(Suppl 2):71-77. doi: 10.3899/jrheum.2023-0537. Epub 2023 Aug 1. J Rheumatol. 2023. PMID: 37527861
TNFR2 Depletion Reduces Psoriatic Inflammation in Mice by Downregulating Specific Dendritic Cell Populations in Lymph Nodes and Inhibiting IL-23/IL-17 Pathways.
Chandrasekharan UM, Kaur R, Harvey JE, Braley C, Rai V, Lee M, de Windt N, Hsieh J, Jaini R, Bayik D, Scheraga RG, Fernandez AP, DiCorleto PE, Husni ME. Chandrasekharan UM, et al. Among authors: husni me. J Invest Dermatol. 2022 Aug;142(8):2159-2172.e9. doi: 10.1016/j.jid.2021.12.036. Epub 2022 Jan 26. J Invest Dermatol. 2022. PMID: 35090950 Free PMC article.
131 results