Li X - Search Results

1

Act1 is a negative regulator in T and B cells via direct inhibition of STAT3.

Zhang CJ, Wang C, Jiang M, Gu C, Xiao J, Chen X, Martin BN, Tang F, Yamamoto E, Xian Y, Wang H, Li F, Sartor RB, Smith H, Husni ME, Shi FD, Gao J, Carman J, Dongre A, McKarns SC, Coppieters K, Jørgensen TN, Leonard WJ, Li X. Zhang CJ, et al. Among authors: li f, li x. Nat Commun. 2018 Jul 16;9(1):2745. doi: 10.1038/s41467-018-04974-3. Nat Commun. 2018. PMID: 30013031 Free PMC article.

2

SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling.

Wald D, Qin J, Zhao Z, Qian Y, Naramura M, Tian L, Towne J, Sims JE, Stark GR, Li X. Wald D, et al. Among authors: li x. Nat Immunol. 2003 Sep;4(9):920-7. doi: 10.1038/ni968. Epub 2003 Aug 17. Nat Immunol. 2003. PMID: 12925853

3

Act1, a negative regulator in CD40- and BAFF-mediated B cell survival.

Qian Y, Qin J, Cui G, Naramura M, Snow EC, Ware CF, Fairchild RL, Omori SA, Rickert RC, Scott M, Kotzin BL, Li X. Qian Y, et al. Among authors: li x. Immunity. 2004 Oct;21(4):575-87. doi: 10.1016/j.immuni.2004.09.001. Immunity. 2004. PMID: 15485634 Free article.

4

The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease.

Qian Y, Liu C, Hartupee J, Altuntas CZ, Gulen MF, Jane-Wit D, Xiao J, Lu Y, Giltiay N, Liu J, Kordula T, Zhang QW, Vallance B, Swaidani S, Aronica M, Tuohy VK, Hamilton T, Li X. Qian Y, et al. Among authors: li x. Nat Immunol. 2007 Mar;8(3):247-56. doi: 10.1038/ni1439. Epub 2007 Feb 4. Nat Immunol. 2007. PMID: 17277779

5

Act1 modulates autoimmunity through its dual functions in CD40L/BAFF and IL-17 signaling.

Li X. Li X. Cytokine. 2008 Feb;41(2):105-13. doi: 10.1016/j.cyto.2007.09.015. Epub 2007 Dec 3. Cytokine. 2008. PMID: 18061473 Review.

6

Deficiency of Act1, a critical modulator of B cell function, leads to development of Sjögren's syndrome.

Qian Y, Giltiay N, Xiao J, Wang Y, Tian J, Han S, Scott M, Carter R, Jorgensen TN, Li X. Qian Y, et al. Among authors: li x. Eur J Immunol. 2008 Aug;38(8):2219-28. doi: 10.1002/eji.200738113. Eur J Immunol. 2008. PMID: 18624351 Free PMC article.

7

The critical role of epithelial-derived Act1 in IL-17- and IL-25-mediated pulmonary inflammation.

Swaidani S, Bulek K, Kang Z, Liu C, Lu Y, Yin W, Aronica M, Li X. Swaidani S, et al. Among authors: li x. J Immunol. 2009 Feb 1;182(3):1631-40. doi: 10.4049/jimmunol.182.3.1631. J Immunol. 2009. PMID: 19155512 Free PMC article.

8

The essential role of single Ig IL-1 receptor-related molecule/Toll IL-1R8 in regulation of Th2 immune response.

Bulek K, Swaidani S, Qin J, Lu Y, Gulen MF, Herjan T, Min B, Kastelein RA, Aronica M, Kosz-Vnenchak M, Li X. Bulek K, et al. Among authors: li x. J Immunol. 2009 Mar 1;182(5):2601-9. doi: 10.4049/jimmunol.0802729. J Immunol. 2009. PMID: 19234154 Free PMC article.

9

Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.

Liu C, Qian W, Qian Y, Giltiay NV, Lu Y, Swaidani S, Misra S, Deng L, Chen ZJ, Li X. Liu C, et al. Among authors: li x. Sci Signal. 2009 Oct 13;2(92):ra63. doi: 10.1126/scisignal.2000382. Sci Signal. 2009. PMID: 19825828 Free PMC article.

10

Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis.

Kang Z, Altuntas CZ, Gulen MF, Liu C, Giltiay N, Qin H, Liu L, Qian W, Ransohoff RM, Bergmann C, Stohlman S, Tuohy VK, Li X. Kang Z, et al. Among authors: li x. Immunity. 2010 Mar 26;32(3):414-25. doi: 10.1016/j.immuni.2010.03.004. Epub 2010 Mar 18. Immunity. 2010. PMID: 20303295 Free PMC article.

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