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Act1 is a negative regulator in T and B cells via direct inhibition of STAT3.
Zhang CJ, Wang C, Jiang M, Gu C, Xiao J, Chen X, Martin BN, Tang F, Yamamoto E, Xian Y, Wang H, Li F, Sartor RB, Smith H, Husni ME, Shi FD, Gao J, Carman J, Dongre A, McKarns SC, Coppieters K, Jørgensen TN, Leonard WJ, Li X. Zhang CJ, et al. Among authors: xian y. Nat Commun. 2018 Jul 16;9(1):2745. doi: 10.1038/s41467-018-04974-3. Nat Commun. 2018. PMID: 30013031 Free PMC article.
Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5-/- mice.
Li Y, Tinoco R, Elmén L, Segota I, Xian Y, Fujita Y, Sahu A, Zarecki R, Marie K, Feng Y, Khateb A, Frederick DT, Ashkenazi SK, Kim H, Perez EG, Day CP, Segura Muñoz RS, Schmaltz R, Yooseph S, Tam MA, Zhang T, Avitan-Hersh E, Tzur L, Roizman S, Boyango I, Bar-Sela G, Orian A, Kaufman RJ, Bosenberg M, Goding CR, Baaten B, Levesque MP, Dummer R, Brown K, Merlino G, Ruppin E, Flaherty K, Ramer-Tait A, Long T, Peterson SN, Bradley LM, Ronai ZA. Li Y, et al. Among authors: xian y. Nat Commun. 2019 Apr 2;10(1):1492. doi: 10.1038/s41467-019-09525-y. Nat Commun. 2019. PMID: 30940817 Free PMC article.
Prebiotic-Induced Anti-tumor Immunity Attenuates Tumor Growth.
Li Y, Elmén L, Segota I, Xian Y, Tinoco R, Feng Y, Fujita Y, Segura Muñoz RR, Schmaltz R, Bradley LM, Ramer-Tait A, Zarecki R, Long T, Peterson SN, Ronai ZA. Li Y, et al. Among authors: xian y. Cell Rep. 2020 Feb 11;30(6):1753-1766.e6. doi: 10.1016/j.celrep.2020.01.035. Cell Rep. 2020. PMID: 32049008 Free PMC article.
Stearidonic-Enriched Soybean Oil Modulates Obesity, Glucose Metabolism, and Fatty Acid Profiles Independently of Akkermansia muciniphila.
Segura Munoz RR, Quach T, Gomes-Neto JC, Xian Y, Pena PA, Weier S, Pellizzon MA, Kittana H, Cody LA, Geis AL, Heck K, Schmaltz RJ, Bindels LB, Cahoon EB, Benson AK, Clemente TE, Ramer-Tait AE. Segura Munoz RR, et al. Among authors: xian y. Mol Nutr Food Res. 2020 Sep;64(17):e2000162. doi: 10.1002/mnfr.202000162. Epub 2020 Jul 26. Mol Nutr Food Res. 2020. PMID: 32656952 Free PMC article.
Wild primate microbiomes prevent weight gain in germ-free mice.
Sidiropoulos DN, Al-Ghalith GA, Shields-Cutler RR, Ward TL, Johnson AJ, Vangay P, Knights D, Kashyap PC, Xian Y, Ramer-Tait AE, Clayton JB. Sidiropoulos DN, et al. Among authors: xian y. Anim Microbiome. 2020 May 7;2(1):16. doi: 10.1186/s42523-020-00033-9. Anim Microbiome. 2020. PMID: 33499991 Free PMC article.
926 results