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Page 1
Generation and Characterization of an IgG4 Monomeric Fc Platform.
Shan L, Colazet M, Rosenthal KL, Yu XQ, Bee JS, Ferguson A, Damschroder MM, Wu H, Dall'Acqua WF, Tsui P, Oganesyan V. Shan L, et al. PLoS One. 2016 Aug 1;11(8):e0160345. doi: 10.1371/journal.pone.0160345. eCollection 2016. PLoS One. 2016. PMID: 27479095 Free PMC article.
Multimechanistic Monoclonal Antibodies (MAbs) Targeting Staphylococcus aureus Alpha-Toxin and Clumping Factor A: Activity and Efficacy Comparisons of a MAb Combination and an Engineered Bispecific Antibody Approach.
Tkaczyk C, Kasturirangan S, Minola A, Jones-Nelson O, Gunter V, Shi YY, Rosenthal K, Aleti V, Semenova E, Warrener P, Tabor D, Stover CK, Corti D, Rainey G, Sellman BR. Tkaczyk C, et al. Among authors: rosenthal k. Antimicrob Agents Chemother. 2017 Jul 25;61(8):e00629-17. doi: 10.1128/AAC.00629-17. Print 2017 Aug. Antimicrob Agents Chemother. 2017. PMID: 28584141 Free PMC article.
Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody.
Oganesyan V, Peng L, Bee JS, Li J, Perry SR, Comer F, Xu L, Cook K, Senthil K, Clarke L, Rosenthal K, Gao C, Damschroder M, Wu H, Dall'Acqua W. Oganesyan V, et al. Among authors: rosenthal k. J Biol Chem. 2018 Jun 1;293(22):8439-8448. doi: 10.1074/jbc.M117.818013. Epub 2018 Apr 18. J Biol Chem. 2018. PMID: 29669810 Free PMC article.
Alanine Scanning Mutagenesis of the MEDI4893 (Suvratoxumab) Epitope Reduces Alpha Toxin Lytic Activity In Vitro and Staphylococcus aureus Fitness in Infection Models.
Tkaczyk C, Semenova E, Shi YY, Rosenthal K, Oganesyan V, Warrener P, Stover CK, Sellman BR. Tkaczyk C, et al. Among authors: rosenthal k. Antimicrob Agents Chemother. 2018 Oct 24;62(11):e01033-18. doi: 10.1128/AAC.01033-18. Print 2018 Nov. Antimicrob Agents Chemother. 2018. PMID: 30150481 Free PMC article.
Long-acting antibody ligand mimetics for HER4-selective agonism.
Shan L, Cook KM, Haskins N, Omar B, Jiang Y, Garcia A, Koksal A, Oganesyan V, Rosenthal K, Wu H, Dall'Acqua WF, Damschroder MM. Shan L, et al. Among authors: rosenthal k. Sci Rep. 2020 Oct 14;10(1):17257. doi: 10.1038/s41598-020-74176-9. Sci Rep. 2020. PMID: 33057063 Free PMC article.
AZD3152 neutralizes SARS-CoV-2 historical and contemporary variants and is protective in hamsters and well tolerated in adults.
Cai Y, Diallo S, Rosenthal K, Ren K, Flores DJ, Dippel A, Oganesyan V, van Dyk N, Chen X, Cantu E, Choudhary R, Sulikowski M, Adissu H, Chawla B, Kar S, Liu C, Dijokaite-Guraliuc A, Mongkolsapaya J, Rajan S, Loo YM, Beavon R, Webber C, Chang LJ, Thomas S, Clegg L, Zhang H, Screaton GR, Philbin N, Harre M, Selim A, Martinez-Alier N, Uriel A, Cohen TS, Perez JL, Esser MT, Blair W, Francica JR. Cai Y, et al. Among authors: rosenthal k. Sci Transl Med. 2024 Jun 26;16(753):eado2817. doi: 10.1126/scitranslmed.ado2817. Epub 2024 Jun 26. Sci Transl Med. 2024. PMID: 38924429
391 results