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A Novel, Fully Human Anti-fucosyl-GM1 Antibody Demonstrates Potent In Vitro and In Vivo Antitumor Activity in Preclinical Models of Small Cell Lung Cancer.
Ponath P, Menezes D, Pan C, Chen B, Oyasu M, Strachan D, LeBlanc H, Sun H, Wang XT, Rangan VS, Deshpande S, Cristea S, Park KS, Sage J, Cardarelli PM. Ponath P, et al. Among authors: leblanc h. Clin Cancer Res. 2018 Oct 15;24(20):5178-5189. doi: 10.1158/1078-0432.CCR-18-0018. Epub 2018 Jul 18. Clin Cancer Res. 2018. PMID: 30021910 Free PMC article.
In vitro characterization of the anti-PD-1 antibody nivolumab, BMS-936558, and in vivo toxicology in non-human primates.
Wang C, Thudium KB, Han M, Wang XT, Huang H, Feingersh D, Garcia C, Wu Y, Kuhne M, Srinivasan M, Singh S, Wong S, Garner N, Leblanc H, Bunch RT, Blanset D, Selby MJ, Korman AJ. Wang C, et al. Among authors: leblanc h. Cancer Immunol Res. 2014 Sep;2(9):846-56. doi: 10.1158/2326-6066.CIR-14-0040. Epub 2014 May 28. Cancer Immunol Res. 2014. PMID: 24872026
A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis.
Yellin M, Paliienko I, Balanescu A, Ter-Vartanian S, Tseluyko V, Xu LA, Tao X, Cardarelli PM, Leblanc H, Nichol G, Ancuta C, Chirieac R, Luo A. Yellin M, et al. Among authors: leblanc h. Arthritis Rheum. 2012 Jun;64(6):1730-9. doi: 10.1002/art.34330. Epub 2011 Dec 6. Arthritis Rheum. 2012. PMID: 22147649 Free article. Clinical Trial.
Immune-stimulating antibody conjugates elicit robust myeloid activation and durable antitumor immunity.
Ackerman SE, Pearson CI, Gregorio JD, Gonzalez JC, Kenkel JA, Hartmann FJ, Luo A, Ho PY, LeBlanc H, Blum LK, Kimmey SC, Luo A, Nguyen ML, Paik JC, Sheu LY, Ackerman B, Lee A, Li H, Melrose J, Laura RP, Ramani VC, Henning KA, Jackson DY, Safina BS, Yonehiro G, Devens BH, Carmi Y, Chapin SJ, Bendall SC, Kowanetz M, Dornan D, Engleman EG, Alonso MN. Ackerman SE, et al. Among authors: leblanc h. Nat Cancer. 2021 Jan;2(1):18-33. doi: 10.1038/s43018-020-00136-x. Epub 2020 Dec 7. Nat Cancer. 2021. PMID: 35121890 Free PMC article.
TWEAK attenuates the transition from innate to adaptive immunity.
Maecker H, Varfolomeev E, Kischkel F, Lawrence D, LeBlanc H, Lee W, Hurst S, Danilenko D, Li J, Filvaroff E, Yang B, Daniel D, Ashkenazi A. Maecker H, et al. Among authors: leblanc h. Cell. 2005 Dec 2;123(5):931-44. doi: 10.1016/j.cell.2005.09.022. Cell. 2005. PMID: 16325585 Free article.
Apo2L/TRAIL and its death and decoy receptors.
LeBlanc HN, Ashkenazi A. LeBlanc HN, et al. Cell Death Differ. 2003 Jan;10(1):66-75. doi: 10.1038/sj.cdd.4401187. Cell Death Differ. 2003. PMID: 12655296 Review.
Interactions between soil and other environmental variables modulate forest expansion and ecotone dynamics in humid savannas of Central Africa.
Sagang LBT, Tcheferi I, Ploton P, Libalah M, Simo-Droissart M, Sirri N, Dauby G, Ngansop E, Bissek JP, Kamdem N, Mofack GII, Zebaze D, Leblanc H, Djonko F, Sonké B, Barbier N, Couteron P. Sagang LBT, et al. Among authors: leblanc h. Proc Biol Sci. 2024 Oct;291(2033):20241120. doi: 10.1098/rspb.2024.1120. Epub 2024 Oct 30. Proc Biol Sci. 2024. PMID: 39471853 Free PMC article.
RluA is the major mRNA pseudouridine synthase in Escherichia coli.
Schaening-Burgos C, LeBlanc H, Fagre C, Li GW, Gilbert WV. Schaening-Burgos C, et al. Among authors: leblanc h. PLoS Genet. 2024 Sep 6;20(9):e1011100. doi: 10.1371/journal.pgen.1011100. eCollection 2024 Sep. PLoS Genet. 2024. PMID: 39241085 Free PMC article.
147 results