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HSos1 contains a new amino-terminal regulatory motif with specific binding affinity for its pleckstrin homology domain.
Jorge R, Zarich N, Oliva JL, Azañedo M, Martínez N, de la Cruz X, Rojas JM. Jorge R, et al. Among authors: rojas jm. J Biol Chem. 2002 Nov 15;277(46):44171-9. doi: 10.1074/jbc.M204423200. Epub 2002 Sep 9. J Biol Chem. 2002. Retraction in: J Biol Chem. 2018 Jul 20;293(29):11650. doi: 10.1074/jbc.W118.004643 PMID: 12223473 Free article. Retracted.
The P34G mutation reduces the transforming activity of K-Ras and N-Ras in NIH 3T3 cells but not of H-Ras.
Oliva JL, Zarich N, Martínez N, Jorge R, Castrillo A, Azañedo M, García-Vargas S, Gutiérrez-Eisman S, Juarranz A, Boscá L, Gutkind JS, Rojas JM. Oliva JL, et al. Among authors: rojas jm. J Biol Chem. 2004 Aug 6;279(32):33480-91. doi: 10.1074/jbc.M404058200. Epub 2004 Jun 4. J Biol Chem. 2004. Retraction in: J Biol Chem. 2018 Jul 20;293(29):11651. doi: 10.1074/jbc.W118.004644 PMID: 15181015 Free article. Retracted.
Grb2 is a negative modulator of the intrinsic Ras-GEF activity of hSos1.
Zarich N, Oliva JL, Martínez N, Jorge R, Ballester A, Gutiérrez-Eisman S, García-Vargas S, Rojas JM. Zarich N, et al. Among authors: rojas jm. Mol Biol Cell. 2006 Aug;17(8):3591-7. doi: 10.1091/mbc.e05-12-1104. Epub 2006 Jun 7. Mol Biol Cell. 2006. PMID: 16760435 Free PMC article.
E1a gene expression blocks the ERK1/2 signaling pathway by promoting nuclear localization and MKP up-regulation: implication in v-H-Ras-induced senescence.
Callejas-Valera JL, Guinea-Viniegra J, Ramírez-Castillejo C, Recio JA, Galan-Moya E, Martinez N, Rojas JM, Ramón y Cajal S, Sánchez-Prieto R. Callejas-Valera JL, et al. Among authors: rojas jm. J Biol Chem. 2008 May 9;283(19):13450-8. doi: 10.1074/jbc.M709230200. Epub 2008 Mar 3. J Biol Chem. 2008. PMID: 18316372 Free article.
Immortalized mouse mammary fibroblasts lacking dioxin receptor have impaired tumorigenicity in a subcutaneous mouse xenograft model.
Mulero-Navarro S, Pozo-Guisado E, Pérez-Mancera PA, Alvarez-Barrientos A, Catalina-Fernández I, Hernández-Nieto E, Sáenz-Santamaria J, Martínez N, Rojas JM, Sánchez-García I, Fernández-Salguero PM. Mulero-Navarro S, et al. Among authors: rojas jm. J Biol Chem. 2005 Aug 5;280(31):28731-41. doi: 10.1074/jbc.M504538200. Epub 2005 Jun 9. J Biol Chem. 2005. PMID: 15946950 Free article.
131 results