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Page 1
HSos1 contains a new amino-terminal regulatory motif with specific binding affinity for its pleckstrin homology domain.
Jorge R, Zarich N, Oliva JL, Azañedo M, Martínez N, de la Cruz X, Rojas JM. Jorge R, et al. Among authors: zarich n. J Biol Chem. 2002 Nov 15;277(46):44171-9. doi: 10.1074/jbc.M204423200. Epub 2002 Sep 9. J Biol Chem. 2002. Retraction in: J Biol Chem. 2018 Jul 20;293(29):11650. doi: 10.1074/jbc.W118.004643 PMID: 12223473 Free article. Retracted.
The P34G mutation reduces the transforming activity of K-Ras and N-Ras in NIH 3T3 cells but not of H-Ras.
Oliva JL, Zarich N, Martínez N, Jorge R, Castrillo A, Azañedo M, García-Vargas S, Gutiérrez-Eisman S, Juarranz A, Boscá L, Gutkind JS, Rojas JM. Oliva JL, et al. Among authors: zarich n. J Biol Chem. 2004 Aug 6;279(32):33480-91. doi: 10.1074/jbc.M404058200. Epub 2004 Jun 4. J Biol Chem. 2004. Retraction in: J Biol Chem. 2018 Jul 20;293(29):11651. doi: 10.1074/jbc.W118.004644 PMID: 15181015 Free article. Retracted.
Grb2 is a negative modulator of the intrinsic Ras-GEF activity of hSos1.
Zarich N, Oliva JL, Martínez N, Jorge R, Ballester A, Gutiérrez-Eisman S, García-Vargas S, Rojas JM. Zarich N, et al. Mol Biol Cell. 2006 Aug;17(8):3591-7. doi: 10.1091/mbc.e05-12-1104. Epub 2006 Jun 7. Mol Biol Cell. 2006. PMID: 16760435 Free PMC article.
Shoc2/Sur8 protein regulates neurite outgrowth.
Leon G, Sanchez-Ruiloba L, Perez-Rodriguez A, Gragera T, Martinez N, Hernandez S, Anta B, Calero O, Garcia-Dominguez CA, Dura LM, Peña-Jimenez D, Castro J, Zarich N, Sanchez-Gomez P, Calero M, Iglesias T, Oliva JL, Rojas JM. Leon G, et al. Among authors: zarich n. PLoS One. 2014 Dec 16;9(12):e114837. doi: 10.1371/journal.pone.0114837. eCollection 2014. PLoS One. 2014. PMID: 25514808 Free PMC article.
PKD phosphorylation and COP9/Signalosome modulate intracellular Spry2 protein stability.
Martínez N, Gragera T, de Lucas MP, Cámara AB, Ballester A, Anta B, Fernández-Medarde A, López-Briones T, Ortega J, Peña-Jiménez D, Barbáchano A, Montero-Calle A, Cordero V, Barderas R, Iglesias T, Yunta M, Oliva JL, Muñoz A, Santos E, Zarich N, Rojas-Cabañeros JM. Martínez N, et al. Among authors: zarich n. Oncogenesis. 2023 Apr 12;12(1):20. doi: 10.1038/s41389-023-00465-3. Oncogenesis. 2023. PMID: 37045830 Free PMC article.
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