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Identification of small molecule allosteric modulators of 5,10-methylenetetrahydrofolate reductase (MTHFR) by targeting its unique regulatory domain.
Bezerra GA, Holenstein A, Foster WR, Xie B, Hicks KG, Bürer C, Lutz S, Mukherjee A, Sarkar D, Bhattacharya D, Rutter J, Talukdar A, Brown PJ, Luo M, Shi L, Froese DS, Yue WW. Bezerra GA, et al. Among authors: yue ww. Biochimie. 2021 Apr;183:100-107. doi: 10.1016/j.biochi.2021.01.007. Epub 2021 Jan 18. Biochimie. 2021. PMID: 33476699 Free PMC article.
Structure and activation mechanism of the human liver-type glutaminase GLS2.
Ferreira IM, Quesñay JEN, Bastos AC, Rodrigues CT, Vollmar M, Krojer T, Strain-Damerell C, Burgess-Brown NA, von Delft F, Yue WW, Dias SM, Ambrosio AL. Ferreira IM, et al. Among authors: yue ww. Biochimie. 2021 Jun;185:96-104. doi: 10.1016/j.biochi.2021.03.009. Epub 2021 Mar 18. Biochimie. 2021. PMID: 33746066 Free PMC article.
Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Kelly JJ, Tranter D, Pardon E, Chi G, Kramer H, Happonen L, Knee KM, Janz JM, Steyaert J, Bulawa C, Paavilainen VO, Huiskonen JT, Yue WW. Kelly JJ, et al. Among authors: yue ww. Nat Struct Mol Biol. 2022 May;29(5):420-429. doi: 10.1038/s41594-022-00755-1. Epub 2022 Apr 21. Nat Struct Mol Biol. 2022. PMID: 35449234 Free PMC article.
159 results