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VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPARγ- and CB2 receptor-dependent pathways.
Del Rio C, Cantarero I, Palomares B, Gómez-Cañas M, Fernández-Ruiz J, Pavicic C, García-Martín A, Luz Bellido M, Ortega-Castro R, Pérez-Sánchez C, López-Pedrera C, Appendino G, Calzado MA, Muñoz E. Del Rio C, et al. Br J Pharmacol. 2018 Oct;175(19):3813-3831. doi: 10.1111/bph.14450. Epub 2018 Aug 23. Br J Pharmacol. 2018. PMID: 30033591 Free PMC article.
Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1.
Casares L, García V, Garrido-Rodríguez M, Millán E, Collado JA, García-Martín A, Peñarando J, Calzado MA, de la Vega L, Muñoz E. Casares L, et al. Redox Biol. 2020 Jan;28:101321. doi: 10.1016/j.redox.2019.101321. Epub 2019 Sep 5. Redox Biol. 2020. PMID: 31518892 Free PMC article.
Cannabinoids in Metabolic Syndrome and Cardiac Fibrosis.
Navarrete C, Garcia-Martin A, DeMesa J, Muñoz E. Navarrete C, et al. Curr Hypertens Rep. 2020 Oct 21;22(12):98. doi: 10.1007/s11906-020-01112-7. Curr Hypertens Rep. 2020. PMID: 33089434 Review.
Neuroprotection with the cannabigerol quinone derivative VCE-003.2 and its analogs CBGA-Q and CBGA-Q-Salt in Parkinson's disease using 6-hydroxydopamine-lesioned mice.
Burgaz S, García C, Gómez-Cañas M, Navarrete C, García-Martín A, Rolland A, Del Río C, Casarejos MJ, Muñoz E, Gonzalo-Consuegra C, Muñoz E, Fernández-Ruiz J. Burgaz S, et al. Mol Cell Neurosci. 2021 Jan;110:103583. doi: 10.1016/j.mcn.2020.103583. Epub 2020 Dec 16. Mol Cell Neurosci. 2021. PMID: 33338634
Cannabidiol and Other Cannabinoids in Demyelinating Diseases.
Navarrete C, García-Martín A, Rolland A, DeMesa J, Muñoz E. Navarrete C, et al. Int J Mol Sci. 2021 Mar 15;22(6):2992. doi: 10.3390/ijms22062992. Int J Mol Sci. 2021. PMID: 33804243 Free PMC article. Review.
253 results