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Cytokines tumor necrosis factor-α and interferon-γ induce pancreatic β-cell apoptosis through STAT1-mediated Bim protein activation.
Barthson J, Germano CM, Moore F, Maida A, Drucker DJ, Marchetti P, Gysemans C, Mathieu C, Nuñez G, Jurisicova A, Eizirik DL, Gurzov EN. Barthson J, et al. Among authors: gurzov en. J Biol Chem. 2011 Nov 11;286(45):39632-43. doi: 10.1074/jbc.M111.253591. Epub 2011 Sep 21. J Biol Chem. 2011. PMID: 21937453 Free PMC article.
JunB protects β-cells from lipotoxicity via the XBP1-AKT pathway.
Cunha DA, Gurzov EN, Naamane N, Ortis F, Cardozo AK, Bugliani M, Marchetti P, Eizirik DL, Cnop M. Cunha DA, et al. Among authors: gurzov en. Cell Death Differ. 2014 Aug;21(8):1313-24. doi: 10.1038/cdd.2014.53. Epub 2014 May 2. Cell Death Differ. 2014. PMID: 24786832 Free PMC article.
59 results