Kogame A - Search Results

1

Investigation of disposition for TAK-448, a synthetic peptide of kisspeptin analog, in rats and dogs using the radiolabeled TAK-448 suitable for pharmacokinetic study.

Moriya Y, Kogame A, Tagawa Y, Morohashi A, Kondo T, Asahi S. Moriya Y, et al. Among authors: kogame a. Xenobiotica. 2019 Jul;49(7):833-839. doi: 10.1080/00498254.2018.1499152. Epub 2018 Sep 12. Xenobiotica. 2019. PMID: 30044673

2

Evaluation of low background liquid scintillation counter for non-clinical ADME studies.

Onishi A, Kogame A, Tagawa Y, Kondo T, Asahi S. Onishi A, et al. Among authors: kogame a. Xenobiotica. 2013 Jun;43(6):520-6. doi: 10.3109/00498254.2012.744861. Epub 2012 Dec 21. Xenobiotica. 2013. PMID: 23256624

3

Disposition and metabolism of TAK-438 (vonoprazan fumarate), a novel potassium-competitive acid blocker, in rats and dogs.

Kogame A, Takeuchi T, Nonaka M, Yamasaki H, Kawaguchi N, Bernards A, Tagawa Y, Morohashi A, Kondo T, Moriwaki T, Asahi S. Kogame A, et al. Xenobiotica. 2017 Mar;47(3):255-266. doi: 10.1080/00498254.2016.1182667. Epub 2016 May 26. Xenobiotica. 2017. PMID: 27225050

4

Disposition and metabolism of the G protein-coupled receptor 40 agonist TAK-875 (fasiglifam) in rats, dogs, and humans.

Kogame A, Lee R, Pan L, Sudo M, Nonaka M, Moriya Y, Higuchi T, Tagawa Y. Kogame A, et al. Xenobiotica. 2019 Apr;49(4):433-445. doi: 10.1080/00498254.2018.1453100. Epub 2018 Apr 5. Xenobiotica. 2019. PMID: 29557709 Clinical Trial.

5

The Enhancement of Subcutaneous First-Pass Metabolism Causes Nonlinear Pharmacokinetics of TAK-448 after a Single Subcutaneous Administration to Rats.

Moriya Y, Kogame A, Tagawa Y, Morohashi A, Kondo T, Asahi S, Benet LZ. Moriya Y, et al. Among authors: kogame a. Drug Metab Dispos. 2019 Sep;47(9):1004-1012. doi: 10.1124/dmd.119.087148. Epub 2019 Jun 14. Drug Metab Dispos. 2019. PMID: 31201213

6

Pharmacokinetic and pharmacodynamic modeling of hedgehog inhibitor TAK-441 for the inhibition of Gli1 messenger RNA expression and antitumor efficacy in xenografted tumor model mice.

Kogame A, Tagawa Y, Shibata S, Tojo H, Miyamoto M, Tohyama K, Kondo T, Prakash S, Shyu WC, Asahi S. Kogame A, et al. Drug Metab Dispos. 2013 Apr;41(4):727-34. doi: 10.1124/dmd.112.049650. Epub 2013 Jan 8. Drug Metab Dispos. 2013. PMID: 23298863

7

Influence of the pharmacokinetic profile on the plasma glucose lowering effect of the PPARγ agonist pioglitazone in Wistar fatty rats.

Goto A, Tagawa Y, Kimura Y, Kogame A, Moriya Y, Amano N. Goto A, et al. Among authors: kogame a. Biopharm Drug Dispos. 2017 Sep;38(6):381-388. doi: 10.1002/bdd.2076. Epub 2017 May 28. Biopharm Drug Dispos. 2017. PMID: 28294376

8

Usefulness of pharmacokinetic/efficacy analysis of an investigational kisspeptin analog, TAK-448, in quantitatively evaluating anti-tumor growth effect in the rat VCaP androgen-sensitive prostate cancer model.

Ishikawa K, Tanaka A, Kogame A, Watanabe T, Tagawa Y, Matsui H. Ishikawa K, et al. Among authors: kogame a. Eur J Pharmacol. 2018 Jun 5;828:126-134. doi: 10.1016/j.ejphar.2018.03.032. Epub 2018 Mar 23. Eur J Pharmacol. 2018. PMID: 29580912

9

Characterization of Fasiglifam-Related Liver Toxicity in Dogs.

Kogame A, Moriya Y, Mori I, Pan L, Morohashi A, Ebihara T, Fukui H, Tagawa Y, Benet LZ. Kogame A, et al. Drug Metab Dispos. 2019 May;47(5):525-534. doi: 10.1124/dmd.118.084889. Epub 2019 Feb 14. Drug Metab Dispos. 2019. PMID: 30765394

10

Development, validation and application of the liquid chromatography tandem mass spectrometry method for simultaneous quantification of azilsartan medoxomil (TAK-491), azilsartan (TAK-536), and its 2 metabolites in human plasma.

Kuze Y, Kogame A, Jinno F, Kondo T, Asahi S. Kuze Y, et al. Among authors: kogame a. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Sep 15;1001:174-81. doi: 10.1016/j.jchromb.2015.07.047. Epub 2015 Jul 30. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 26279009

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

21 results

Search Page

Filters