Abdelrahman A - Search Results

1

3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17.

Baqi Y, Pillaiyar T, Abdelrahman A, Kaufmann O, Alshaibani S, Rafehi M, Ghasimi S, Akkari R, Ritter K, Simon K, Spinrath A, Kostenis E, Zhao Q, Köse M, Namasivayam V, Müller CE. Baqi Y, et al. Among authors: abdelrahman a. J Med Chem. 2018 Sep 27;61(18):8136-8154. doi: 10.1021/acs.jmedchem.7b01768. Epub 2018 Sep 5. J Med Chem. 2018. PMID: 30048589

2

Cloning and functional expression of a novel Gi protein-coupled receptor for adenine from mouse brain.

von Kügelgen I, Schiedel AC, Hoffmann K, Alsdorf BB, Abdelrahman A, Müller CE. von Kügelgen I, et al. Among authors: abdelrahman a. Mol Pharmacol. 2008 Feb;73(2):469-77. doi: 10.1124/mol.107.037069. Epub 2007 Nov 1. Mol Pharmacol. 2008. PMID: 17975009

3

Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family.

Borrmann T, Abdelrahman A, Volpini R, Lambertucci C, Alksnis E, Gorzalka S, Knospe M, Schiedel AC, Cristalli G, Müller CE. Borrmann T, et al. Among authors: abdelrahman a. J Med Chem. 2009 Oct 8;52(19):5974-89. doi: 10.1021/jm9006356. J Med Chem. 2009. PMID: 19731917

4

Extracellular NAD(+) induces a rise in [Ca(2+)](i) in activated human monocytes via engagement of P2Y(1) and P2Y(11) receptors.

Klein C, Grahnert A, Abdelrahman A, Müller CE, Hauschildt S. Klein C, et al. Among authors: abdelrahman a. Cell Calcium. 2009 Oct;46(4):263-72. doi: 10.1016/j.ceca.2009.08.004. Epub 2009 Sep 11. Cell Calcium. 2009. PMID: 19748117

5

N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists.

Hernandez-Olmos V, Abdelrahman A, El-Tayeb A, Freudendahl D, Weinhausen S, Müller CE. Hernandez-Olmos V, et al. Among authors: abdelrahman a. J Med Chem. 2012 Nov 26;55(22):9576-88. doi: 10.1021/jm300845v. Epub 2012 Nov 1. J Med Chem. 2012. PMID: 23075067

6

The rat adenine receptor: pharmacological characterization and mutagenesis studies to investigate its putative ligand binding site.

Knospe M, Müller CE, Rosa P, Abdelrahman A, von Kügelgen I, Thimm D, Schiedel AC. Knospe M, et al. Among authors: abdelrahman a. Purinergic Signal. 2013 Sep;9(3):367-81. doi: 10.1007/s11302-013-9355-6. Epub 2013 Feb 15. Purinergic Signal. 2013. PMID: 23413038 Free PMC article.

7

Characterization of new G protein-coupled adenine receptors in mouse and hamster.

Thimm D, Knospe M, Abdelrahman A, Moutinho M, Alsdorf BB, von Kügelgen I, Schiedel AC, Müller CE. Thimm D, et al. Among authors: abdelrahman a. Purinergic Signal. 2013 Sep;9(3):415-26. doi: 10.1007/s11302-013-9360-9. Epub 2013 Apr 23. Purinergic Signal. 2013. PMID: 23608776 Free PMC article.

8

Carbamazepine derivatives with P2X4 receptor-blocking activity.

Tian M, Abdelrahman A, Weinhausen S, Hinz S, Weyer S, Dosa S, El-Tayeb A, Müller CE. Tian M, et al. Among authors: abdelrahman a. Bioorg Med Chem. 2014 Feb 1;22(3):1077-88. doi: 10.1016/j.bmc.2013.12.035. Epub 2013 Dec 25. Bioorg Med Chem. 2014. PMID: 24411477

9

Development of Polar Adenosine A2A Receptor Agonists for Inflammatory Bowel Disease: Synergism with A2B Antagonists.

El-Tayeb A, Michael S, Abdelrahman A, Behrenswerth A, Gollos S, Nieber K, Müller CE. El-Tayeb A, et al. Among authors: abdelrahman a. ACS Med Chem Lett. 2011 Oct 10;2(12):890-5. doi: 10.1021/ml200189u. eCollection 2011 Dec 8. ACS Med Chem Lett. 2011. PMID: 24900277 Free PMC article.

10

α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors.

Bhattarai S, Freundlieb M, Pippel J, Meyer A, Abdelrahman A, Fiene A, Lee SY, Zimmermann H, Yegutkin GG, Sträter N, El-Tayeb A, Müller CE. Bhattarai S, et al. Among authors: abdelrahman a. J Med Chem. 2015 Aug 13;58(15):6248-63. doi: 10.1021/acs.jmedchem.5b00802. Epub 2015 Jul 30. J Med Chem. 2015. PMID: 26147331

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