Rafehi M - Search Results

1

3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17.

Baqi Y, Pillaiyar T, Abdelrahman A, Kaufmann O, Alshaibani S, Rafehi M, Ghasimi S, Akkari R, Ritter K, Simon K, Spinrath A, Kostenis E, Zhao Q, Köse M, Namasivayam V, Müller CE. Baqi Y, et al. Among authors: rafehi m. J Med Chem. 2018 Sep 27;61(18):8136-8154. doi: 10.1021/acs.jmedchem.7b01768. Epub 2018 Sep 5. J Med Chem. 2018. PMID: 30048589

2

Stereoselectivity in the Membrane Transport of Phenylethylamine Derivatives by Human Monoamine Transporters and Organic Cation Transporters 1, 2, and 3.

Gebauer L, Rafehi M, Brockmöller J. Gebauer L, et al. Among authors: rafehi m. Biomolecules. 2022 Oct 18;12(10):1507. doi: 10.3390/biom12101507. Biomolecules. 2022. PMID: 36291716 Free PMC article.

3

8-Substituted 1,3-dimethyltetrahydropyrazino[2,1-f]purinediones: Water-soluble adenosine receptor antagonists and monoamine oxidase B inhibitors.

Brunschweiger A, Koch P, Schlenk M, Rafehi M, Radjainia H, Küppers P, Hinz S, Pineda F, Wiese M, Hockemeyer J, Heer J, Denonne F, Müller CE. Brunschweiger A, et al. Among authors: rafehi m. Bioorg Med Chem. 2016 Nov 1;24(21):5462-5480. doi: 10.1016/j.bmc.2016.09.003. Epub 2016 Sep 3. Bioorg Med Chem. 2016. PMID: 27658798

4

Synthesis, characterization, and in vitro evaluation of the selective P2Y₂ receptor antagonist AR-C118925.

Rafehi M, Burbiel JC, Attah IY, Abdelrahman A, Müller CE. Rafehi M, et al. Purinergic Signal. 2017 Mar;13(1):89-103. doi: 10.1007/s11302-016-9542-3. Epub 2016 Oct 20. Purinergic Signal. 2017. PMID: 27766552 Free PMC article.

5

Development of Potent and Selective Antagonists for the UTP-Activated P2Y₄ Receptor.

Rafehi M, Malik EM, Neumann A, Abdelrahman A, Hanck T, Namasivayam V, Müller CE, Baqi Y. Rafehi M, et al. J Med Chem. 2017 Apr 13;60(7):3020-3038. doi: 10.1021/acs.jmedchem.7b00030. Epub 2017 Mar 30. J Med Chem. 2017. PMID: 28306255

6

Molecular Recognition of Agonists and Antagonists by the Nucleotide-Activated G Protein-Coupled P2Y₂ Receptor.

Rafehi M, Neumann A, Baqi Y, Malik EM, Wiese M, Namasivayam V, Müller CE. Rafehi M, et al. J Med Chem. 2017 Oct 26;60(20):8425-8440. doi: 10.1021/acs.jmedchem.7b00854. Epub 2017 Oct 10. J Med Chem. 2017. PMID: 28938069

7

Adenosine A_2A receptor ligand recognition and signaling is blocked by A_2B receptors.

Hinz S, Navarro G, Borroto-Escuela D, Seibt BF, Ammon YC, de Filippo E, Danish A, Lacher SK, Červinková B, Rafehi M, Fuxe K, Schiedel AC, Franco R, Müller CE. Hinz S, et al. Among authors: rafehi m. Oncotarget. 2018 Feb 6;9(17):13593-13611. doi: 10.18632/oncotarget.24423. eCollection 2018 Mar 2. Oncotarget. 2018. PMID: 29568380 Free PMC article.

8

Tools and drugs for uracil nucleotide-activated P2Y receptors.

Rafehi M, Müller CE. Rafehi M, et al. Pharmacol Ther. 2018 Oct;190:24-80. doi: 10.1016/j.pharmthera.2018.04.002. Epub 2018 Apr 13. Pharmacol Ther. 2018. PMID: 29660366 Review.

9

Adenine-(methoxy)-ethoxy-P_α,α-dithio-triphosphate inhibits pathologic calcium pyrophosphate deposition in osteoarthritic human chondrocytes.

Nassir M, Mirza S, Arad U, Lee S, Rafehi M, Yaw Attah I, Renn C, Zimmermann H, Pelletier J, Sévigny J, Müller CE, Fischer B. Nassir M, et al. Among authors: rafehi m. Org Biomol Chem. 2019 Nov 27;17(46):9913-9923. doi: 10.1039/c9ob02199j. Org Biomol Chem. 2019. PMID: 31720670

10

Ligand binding and activation of UTP-activated G protein-coupled P2Y₂ and P2Y₄ receptors elucidated by mutagenesis, pharmacological and computational studies.

Attah IY, Neumann A, Al-Hroub H, Rafehi M, Baqi Y, Namasivayam V, Müller CE. Attah IY, et al. Among authors: rafehi m. Biochim Biophys Acta Gen Subj. 2020 Mar;1864(3):129501. doi: 10.1016/j.bbagen.2019.129501. Epub 2019 Dec 5. Biochim Biophys Acta Gen Subj. 2020. PMID: 31812541

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