Sistare FD - Search Results

1

Adverse outcome pathway-driven identification of rat liver tumorigens in short-term assays.

Rooney J, Hill T 3rd, Qin C, Sistare FD, Corton JC. Rooney J, et al. Among authors: sistare fd. Toxicol Appl Pharmacol. 2018 Oct 1;356:99-113. doi: 10.1016/j.taap.2018.07.023. Epub 2018 Jul 23. Toxicol Appl Pharmacol. 2018. PMID: 30048669

2

Quantitative Transcriptional Biomarkers of Xenobiotic Receptor Activation in Rat Liver for the Early Assessment of Drug Safety Liabilities.

Podtelezhnikov AA, Monroe JJ, Aslamkhan AG, Pearson K, Qin C, Tamburino AM, Loboda AP, Glaab WE, Sistare FD, Tanis KQ. Podtelezhnikov AA, et al. Among authors: sistare fd. Toxicol Sci. 2020 May 1;175(1):98-112. doi: 10.1093/toxsci/kfaa026. Toxicol Sci. 2020. PMID: 32119089

3

A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies.

Corton JC, Mitchell CA, Auerbach S, Bushel P, Ellinger-Ziegelbauer H, Escobar PA, Froetschl R, Harrill AH, Johnson K, Klaunig JE, Pandiri AR, Podtelezhnikov AA, Rager JE, Tanis KQ, van der Laan JW, Vespa A, Yauk CL, Pettit SD, Sistare FD. Corton JC, et al. Among authors: sistare fd. Toxicol Sci. 2022 Jun 28;188(1):4-16. doi: 10.1093/toxsci/kfac041. Toxicol Sci. 2022. PMID: 35404422 Free PMC article.

4

Toxicogenomics in drug development: a match made in heaven?

Qin C, Tanis KQ, Podtelezhnikov AA, Glaab WE, Sistare FD, DeGeorge JJ. Qin C, et al. Among authors: sistare fd. Expert Opin Drug Metab Toxicol. 2016 Aug;12(8):847-9. doi: 10.1080/17425255.2016.1175437. Epub 2016 Apr 21. Expert Opin Drug Metab Toxicol. 2016. PMID: 27050123 No abstract available.

5

AhR Activation in Pharmaceutical Development: Applying Liver Gene Expression Biomarker Thresholds to Identify Doses Associated With Tumorigenic Risks in Rats.

Qin C, Aslamkhan AG, Pearson K, Tanis KQ, Podtelezhnikov A, Frank E, Pacchione S, Pippert T, Glaab WE, Sistare FD. Qin C, et al. Among authors: sistare fd. Toxicol Sci. 2019 Sep 1;171(1):46-55. doi: 10.1093/toxsci/kfz125. Toxicol Sci. 2019. PMID: 31127949

6

Evaluation of the Tg.AC transgenic mouse assay for testing the human carcinogenic potential of pharmaceuticals--practical pointers, mechanistic clues, and new questions.

Sistare FD, Thompson KL, Honchel R, DeGeorge J. Sistare FD, et al. Int J Toxicol. 2002 Jan-Feb;21(1):65-79. doi: 10.1080/10915810252826028. Int J Toxicol. 2002. PMID: 11936901 Review.

7

Evaluation of the relative performance of 12 urinary biomarkers for renal safety across 22 rat sensitivity and specificity studies.

Vlasakova K, Erdos Z, Troth SP, McNulty K, Chapeau-Campredon V, Mokrzycki N, Muniappa N, Gu YZ, Holder D, Bailey WJ, Sistare FD, Glaab WE. Vlasakova K, et al. Among authors: sistare fd. Toxicol Sci. 2014 Mar;138(1):3-20. doi: 10.1093/toxsci/kft330. Epub 2013 Dec 21. Toxicol Sci. 2014. PMID: 24361871

8

An evaluation of chronic 6- and 12-month rat toxicology studies as predictors of 2-year tumor outcome.

Reddy MV, Sistare FD, Christensen JS, Deluca JG, Wollenberg GK, Degeorge JJ. Reddy MV, et al. Among authors: sistare fd. Vet Pathol. 2010 Jul;47(4):614-29. doi: 10.1177/0300985810373242. Epub 2010 Jun 1. Vet Pathol. 2010. PMID: 20516294

9

A cross-sector call to improve carcinogenicity risk assessment through use of genomic methodologies.

Yauk CL, Harrill AH, Ellinger-Ziegelbauer H, van der Laan JW, Moggs J, Froetschl R, Sistare F, Pettit S. Yauk CL, et al. Regul Toxicol Pharmacol. 2020 Feb;110:104526. doi: 10.1016/j.yrtph.2019.104526. Epub 2019 Nov 11. Regul Toxicol Pharmacol. 2020. PMID: 31726190 Free PMC article.

10

A Performance Evaluation of Liver and Skeletal Muscle-Specific miRNAs in Rat Plasma to Detect Drug-Induced Injury.

Bailey WJ, Barnum JE, Erdos Z, LaFranco-Scheuch L, Lane P, Vlasakova K, Sistare FD, Glaab WE. Bailey WJ, et al. Among authors: sistare fd. Toxicol Sci. 2019 Mar 1;168(1):110-125. doi: 10.1093/toxsci/kfy282. Toxicol Sci. 2019. PMID: 30496518

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