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Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation.
Cheung SY, Werner M, Esposito L, Troisi F, Cantone V, Liening S, König S, Gerstmeier J, Koeberle A, Bilancia R, Rizza R, Rossi A, Roviezzo F, Temml V, Schuster D, Stuppner H, Schubert-Zsilavecz M, Werz O, Hanke T, Pace S. Cheung SY, et al. Among authors: roviezzo f. Eur J Med Chem. 2018 Aug 5;156:815-830. doi: 10.1016/j.ejmech.2018.07.031. Epub 2018 Jul 25. Eur J Med Chem. 2018. PMID: 30053720
Formulation of Solid Lipid Nanoparticles Loaded with Nociceptin/Orphanin FQ (N/OFQ) and Characterization in a Murine Model of Airway Hyperresponsiveness.
Mirra D, Spaziano G, Esposito R, Santonocito D, Filosa R, Roviezzo F, Malgieri G, D'Abrosca G, Iovino P, Gallelli L, Fattorusso R, Puglia C, D'Agostino B. Mirra D, et al. Among authors: roviezzo f. Pharmaceuticals (Basel). 2022 Sep 29;15(10):1210. doi: 10.3390/ph15101210. Pharmaceuticals (Basel). 2022. PMID: 36297323 Free PMC article.
Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase.
Schaible AM, Filosa R, Temml V, Krauth V, Matteis M, Peduto A, Bruno F, Luderer S, Roviezzo F, Di Mola A, de Rosa M, D'Agostino B, Weinigel C, Barz D, Koeberle A, Pergola C, Schuster D, Werz O. Schaible AM, et al. Among authors: roviezzo f. Br J Pharmacol. 2014 May;171(9):2399-412. doi: 10.1111/bph.12592. Br J Pharmacol. 2014. PMID: 24467325 Free PMC article.
Salvinorin A Inhibits Airway Hyperreactivity Induced by Ovalbumin Sensitization.
Rossi A, Caiazzo E, Bilancia R, Riemma MA, Pagano E, Cicala C, Ialenti A, Zjawiony JK, Izzo AA, Capasso R, Roviezzo F. Rossi A, et al. Among authors: roviezzo f. Front Pharmacol. 2017 Jan 13;7:525. doi: 10.3389/fphar.2016.00525. eCollection 2016. Front Pharmacol. 2017. PMID: 28133450 Free PMC article.
85 results