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Page 1
The exerkine apelin reverses age-associated sarcopenia.
Vinel C, Lukjanenko L, Batut A, Deleruyelle S, Pradère JP, Le Gonidec S, Dortignac A, Geoffre N, Pereira O, Karaz S, Lee U, Camus M, Chaoui K, Mouisel E, Bigot A, Mouly V, Vigneau M, Pagano AF, Chopard A, Pillard F, Guyonnet S, Cesari M, Burlet-Schiltz O, Pahor M, Feige JN, Vellas B, Valet P, Dray C. Vinel C, et al. Among authors: deleruyelle s. Nat Med. 2018 Sep;24(9):1360-1371. doi: 10.1038/s41591-018-0131-6. Epub 2018 Jul 30. Nat Med. 2018. PMID: 30061698 Clinical Trial.
Upregulated Apelin Signaling in Pancreatic Cancer Activates Oncogenic Signaling Pathways to Promote Tumor Development.
Chaves-Almagro C, Auriau J, Dortignac A, Clerc P, Lulka H, Deleruyelle S, Projetti F, Nakhlé J, Frances A, Berta J, Gigoux V, Fourmy D, Dufresne M, Gomez-Brouchet A, Guillermet-Guibert J, Cordelier P, Knibiehler B, Jockers R, Valet P, Audigier Y, Masri B. Chaves-Almagro C, et al. Among authors: deleruyelle s. Int J Mol Sci. 2022 Sep 13;23(18):10600. doi: 10.3390/ijms231810600. Int J Mol Sci. 2022. PMID: 36142542 Free PMC article.
SHP2 drives inflammation-triggered insulin resistance by reshaping tissue macrophage populations.
Paccoud R, Saint-Laurent C, Piccolo E, Tajan M, Dortignac A, Pereira O, Le Gonidec S, Baba I, Gélineau A, Askia H, Branchereau M, Charpentier J, Personnaz J, Branka S, Auriau J, Deleruyelle S, Canouil M, Beton N, Salles JP, Tauber M, Weill J, Froguel P, Neel BG, Araki T, Heymes C, Burcelin R, Castan I, Valet P, Dray C, Gautier EL, Edouard T, Pradère JP, Yart A. Paccoud R, et al. Among authors: deleruyelle s. Sci Transl Med. 2021 Apr 28;13(591):eabe2587. doi: 10.1126/scitranslmed.abe2587. Epub 2021 Apr 28. Sci Transl Med. 2021. PMID: 33910978
Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor.
Personnaz J, Piccolo E, Dortignac A, Iacovoni JS, Mariette J, Rocher V, Polizzi A, Batut A, Deleruyelle S, Bourdens L, Delos O, Combes-Soia L, Paccoud R, Moreau E, Martins F, Clouaire T, Benhamed F, Montagner A, Wahli W, Schwabe RF, Yart A, Castan-Laurell I, Bertrand-Michel J, Burlet-Schiltz O, Postic C, Denechaud PD, Moro C, Legube G, Lee CH, Guillou H, Valet P, Dray C, Pradère JP. Personnaz J, et al. Among authors: deleruyelle s. Sci Adv. 2022 Mar 25;8(12):eabg9055. doi: 10.1126/sciadv.abg9055. Epub 2022 Mar 25. Sci Adv. 2022. PMID: 35333579 Free PMC article.
LEOPARD syndrome-associated SHP2 mutation confers leanness and protection from diet-induced obesity.
Tajan M, Batut A, Cadoudal T, Deleruyelle S, Le Gonidec S, Saint Laurent C, Vomscheid M, Wanecq E, Tréguer K, De Rocca Serra-Nédélec A, Vinel C, Marques MA, Pozzo J, Kunduzova O, Salles JP, Tauber M, Raynal P, Cavé H, Edouard T, Valet P, Yart A. Tajan M, et al. Among authors: deleruyelle s. Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4494-503. doi: 10.1073/pnas.1406107111. Epub 2014 Oct 6. Proc Natl Acad Sci U S A. 2014. PMID: 25288766 Free PMC article.
Piceatannol and resveratrol share inhibitory effects on hydrogen peroxide release, monoamine oxidase and lipogenic activities in adipose tissue, but differ in their antilipolytic properties.
Les F, Deleruyelle S, Cassagnes LE, Boutin JA, Balogh B, Arbones-Mainar JM, Biron S, Marceau P, Richard D, Nepveu F, Mauriège P, Carpéné C. Les F, et al. Among authors: deleruyelle s. Chem Biol Interact. 2016 Oct 25;258:115-25. doi: 10.1016/j.cbi.2016.07.014. Epub 2016 Jul 28. Chem Biol Interact. 2016. PMID: 27475863