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HX600, a synthetic agonist for RXR-Nurr1 heterodimer complex, prevents ischemia-induced neuronal damage.
Loppi S, Kolosowska N, Kärkkäinen O, Korhonen P, Huuskonen M, Grubman A, Dhungana H, Wojciechowski S, Pomeshchik Y, Giordano M, Kagechika H, White A, Auriola S, Koistinaho J, Landreth G, Hanhineva K, Kanninen K, Malm T. Loppi S, et al. Among authors: hanhineva k. Brain Behav Immun. 2018 Oct;73:670-681. doi: 10.1016/j.bbi.2018.07.021. Epub 2018 Jul 29. Brain Behav Immun. 2018. PMID: 30063972 Free PMC article.
Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans.
U-Din M, de Mello VD, Tuomainen M, Raiko J, Niemi T, Fromme T, Klåvus A, Gautier N, Haimilahti K, Lehtonen M, Kristiansen K, Newman JW, Pietiläinen KH, Pihlajamäki J, Amri EZ, Klingenspor M, Nuutila P, Pirinen E, Hanhineva K, Virtanen KA. U-Din M, et al. Among authors: hanhineva k. Cell Rep. 2023 Sep 26;42(9):113131. doi: 10.1016/j.celrep.2023.113131. Epub 2023 Sep 13. Cell Rep. 2023. PMID: 37708023 Free article.
Betaine supplementation causes increase in carnitine metabolites in the muscle and liver of mice fed a high-fat diet as studied by nontargeted LC-MS metabolomics approach.
Pekkinen J, Olli K, Huotari A, Tiihonen K, Keski-Rahkonen P, Lehtonen M, Auriola S, Kolehmainen M, Mykkänen H, Poutanen K, Hanhineva K. Pekkinen J, et al. Among authors: hanhineva k. Mol Nutr Food Res. 2013 Nov;57(11):1959-68. doi: 10.1002/mnfr.201300142. Epub 2013 Jul 19. Mol Nutr Food Res. 2013. PMID: 23868375
Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals.
Tuomainen M, Lindström J, Lehtonen M, Auriola S, Pihlajamäki J, Peltonen M, Tuomilehto J, Uusitupa M, de Mello VD, Hanhineva K. Tuomainen M, et al. Among authors: hanhineva k. Nutr Diabetes. 2018 May 25;8(1):35. doi: 10.1038/s41387-018-0046-9. Nutr Diabetes. 2018. PMID: 29795366 Free PMC article. Clinical Trial.
122 results