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Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model.
Taghibiglou C, Carpentier A, Van Iderstine SC, Chen B, Rudy D, Aiton A, Lewis GF, Adeli K. Taghibiglou C, et al. Among authors: adeli k. J Biol Chem. 2000 Mar 24;275(12):8416-25. doi: 10.1074/jbc.275.12.8416. J Biol Chem. 2000. PMID: 10722675 Free article.
Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and ApoB48-containing lipoprotein overproduction.
Haidari M, Leung N, Mahbub F, Uffelman KD, Kohen-Avramoglu R, Lewis GF, Adeli K. Haidari M, et al. Among authors: adeli k. J Biol Chem. 2002 Aug 30;277(35):31646-55. doi: 10.1074/jbc.M200544200. Epub 2002 Jun 17. J Biol Chem. 2002. PMID: 12070142 Free article.
Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance.
Taghibiglou C, Rashid-Kolvear F, Van Iderstine SC, Le-Tien H, Fantus IG, Lewis GF, Adeli K. Taghibiglou C, et al. Among authors: adeli k. J Biol Chem. 2002 Jan 4;277(1):793-803. doi: 10.1074/jbc.M106737200. Epub 2001 Oct 11. J Biol Chem. 2002. PMID: 11598116 Free article.
Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster.
Carpentier A, Taghibiglou C, Leung N, Szeto L, Van Iderstine SC, Uffelman KD, Buckingham R, Adeli K, Lewis GF. Carpentier A, et al. Among authors: adeli k. J Biol Chem. 2002 Aug 9;277(32):28795-802. doi: 10.1074/jbc.M204568200. Epub 2002 Jun 4. J Biol Chem. 2002. PMID: 12048212 Free article.
Mechanisms targeting apolipoprotein B100 to proteasomal degradation: evidence that degradation is initiated by BiP binding at the N terminus and the formation of a p97 complex at the C terminus.
Rutledge AC, Qiu W, Zhang R, Kohen-Avramoglu R, Nemat-Gorgani N, Adeli K. Rutledge AC, et al. Among authors: adeli k. Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):579-85. doi: 10.1161/ATVBAHA.108.181859. Epub 2009 Jan 22. Arterioscler Thromb Vasc Biol. 2009. PMID: 19164805
399 results