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Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice.
Koestner W, Spanier J, Klause T, Tegtmeyer PK, Becker J, Herder V, Borst K, Todt D, Lienenklaus S, Gerhauser I, Detje CN, Geffers R, Langereis MA, Vondran FWR, Yuan Q, van Kuppeveld FJM, Ott M, Staeheli P, Steinmann E, Baumgärtner W, Wacker F, Kalinke U. Koestner W, et al. Among authors: van kuppeveld fjm. PLoS Pathog. 2018 Aug 3;14(8):e1007235. doi: 10.1371/journal.ppat.1007235. eCollection 2018 Aug. PLoS Pathog. 2018. PMID: 30075026 Free PMC article.
Modification of picornavirus genomic RNA using 'click' chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA.
Langereis MA, Feng Q, Nelissen FH, Virgen-Slane R, van der Heden van Noort GJ, Maciejewski S, Filippov DV, Semler BL, van Delft FL, van Kuppeveld FJ. Langereis MA, et al. Nucleic Acids Res. 2014 Feb;42(4):2473-82. doi: 10.1093/nar/gkt1162. Epub 2013 Nov 15. Nucleic Acids Res. 2014. PMID: 24243841 Free PMC article.
Enterovirus 2Apro targets MDA5 and MAVS in infected cells.
Feng Q, Langereis MA, Lork M, Nguyen M, Hato SV, Lanke K, Emdad L, Bhoopathi P, Fisher PB, Lloyd RE, van Kuppeveld FJ. Feng Q, et al. J Virol. 2014 Mar;88(6):3369-78. doi: 10.1128/JVI.02712-13. Epub 2014 Jan 3. J Virol. 2014. PMID: 24390337 Free PMC article.
Binding of glutathione to enterovirus capsids is essential for virion morphogenesis.
Thibaut HJ, van der Linden L, Jiang P, Thys B, Canela MD, Aguado L, Rombaut B, Wimmer E, Paul A, Pérez-Pérez MJ, van Kuppeveld FJ, Neyts J. Thibaut HJ, et al. PLoS Pathog. 2014 Apr 10;10(4):e1004039. doi: 10.1371/journal.ppat.1004039. eCollection 2014 Apr. PLoS Pathog. 2014. PMID: 24722756 Free PMC article.
264 results