Chen D - Search Results

1

Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice.

Wang Q, Tan Q, Xu W, Kuang L, Zhang B, Wang Z, Ni Z, Su N, Jin M, Li C, Jiang W, Huang J, Li F, Zhu Y, Chen H, Du X, Chen D, Deng C, Qi H, Xie Y, Chen L. Wang Q, et al. Among authors: chen l, chen d, chen h. J Cell Physiol. 2018 Jan;234(1):595-605. doi: 10.1002/jcp.26802. Epub 2018 Aug 5. J Cell Physiol. 2018. PMID: 30078186 Free PMC article.

2

Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice.

Weng T, Yi L, Huang J, Luo F, Wen X, Du X, Chen Q, Deng C, Chen D, Chen L. Weng T, et al. Among authors: chen l, chen q, chen d. Arthritis Rheum. 2012 Dec;64(12):3982-92. doi: 10.1002/art.34645. Arthritis Rheum. 2012. PMID: 22833219 Free PMC article.

3

FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice.

Kuang L, Wu J, Su N, Qi H, Chen H, Zhou S, Xiong Y, Du X, Tan Q, Yang J, Jin M, Luo F, Ouyang J, Zhang B, Wang Z, Jiang W, Chen L, Chen S, Wang Z, Liu P, Yin L, Guo F, Deng C, Chen D, Liu C, Xie Y, Ni Z, Chen L. Kuang L, et al. Among authors: chen l, chen s, chen d, chen h. Ann Rheum Dis. 2020 Jan;79(1):112-122. doi: 10.1136/annrheumdis-2019-215696. Epub 2019 Oct 29. Ann Rheum Dis. 2020. PMID: 31662319

4

A novel FGFR3-binding peptide inhibits FGFR3 signaling and reverses the lethal phenotype of mice mimicking human thanatophoric dysplasia.

Jin M, Yu Y, Qi H, Xie Y, Su N, Wang X, Tan Q, Luo F, Zhu Y, Wang Q, Du X, Xian CJ, Liu P, Huang H, Shen Y, Deng CX, Chen D, Chen L. Jin M, et al. Among authors: chen l, chen d. Hum Mol Genet. 2012 Dec 15;21(26):5443-55. doi: 10.1093/hmg/dds390. Epub 2012 Sep 26. Hum Mol Genet. 2012. PMID: 23014564 Free PMC article.

5

Overexpression of H1 calponin in osteoblast lineage cells leads to a decrease in bone mass by disrupting osteoblast function and promoting osteoclast formation.

Su N, Chen M, Chen S, Li C, Xie Y, Zhu Y, Zhang Y, Zhao L, He Q, Du X, Chen D, Chen L. Su N, et al. Among authors: chen l, chen m, chen s, chen d. J Bone Miner Res. 2013 Mar;28(3):660-71. doi: 10.1002/jbmr.1778. J Bone Miner Res. 2013. PMID: 23044709 Free PMC article.

6

FGFR3 induces degradation of BMP type I receptor to regulate skeletal development.

Qi H, Jin M, Duan Y, Du X, Zhang Y, Ren F, Wang Y, Tian Q, Wang X, Wang Q, Zhu Y, Xie Y, Liu C, Cao X, Mishina Y, Chen D, Deng CX, Chang Z, Chen L. Qi H, et al. Among authors: chen l, chen d. Biochim Biophys Acta. 2014 Jul;1843(7):1237-47. doi: 10.1016/j.bbamcr.2014.03.011. Epub 2014 Mar 20. Biochim Biophys Acta. 2014. PMID: 24657641 Free PMC article.

7

FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling.

Zhou S, Xie Y, Tang J, Huang J, Huang Q, Xu W, Wang Z, Luo F, Wang Q, Chen H, Du X, Shen Y, Chen D, Chen L. Zhou S, et al. Among authors: chen l, chen d, chen h. PLoS Genet. 2015 Jun 19;11(6):e1005214. doi: 10.1371/journal.pgen.1005214. eCollection 2015 Jun. PLoS Genet. 2015. PMID: 26091072 Free PMC article.

8

FGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12-ATG5 conjugate, leading to the delay of cartilage development in achondroplasia.

Wang X, Qi H, Wang Q, Zhu Y, Wang X, Jin M, Tan Q, Huang Q, Xu W, Li X, Kuang L, Tang Y, Du X, Chen D, Chen L. Wang X, et al. Among authors: chen l, chen d. Autophagy. 2015 Nov 2;11(11):1998-2013. doi: 10.1080/15548627.2015.1091551. Autophagy. 2015. PMID: 26491898 Free PMC article.

9

Fgfr3 mutation disrupts chondrogenesis and bone ossification in zebrafish model mimicking CATSHL syndrome partially via enhanced Wnt/β-catenin signaling.

Sun X, Zhang R, Chen H, Du X, Chen S, Huang J, Liu M, Xu M, Luo F, Jin M, Su N, Qi H, Yang J, Tan Q, Zhang D, Ni Z, Liang S, Zhang B, Chen D, Zhang X, Luo L, Chen L, Xie Y. Sun X, et al. Among authors: chen l, chen s, chen d, chen h. Theranostics. 2020 May 30;10(16):7111-7130. doi: 10.7150/thno.45286. eCollection 2020. Theranostics. 2020. PMID: 32641982 Free PMC article.

10

Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway.

Zhang D, Huang J, Sun X, Chen H, Huang S, Yang J, Du X, Tan Q, Luo F, Zhang R, Zhou S, Jiang W, Ni Z, Wang Z, Jin M, Xu M, Li F, Chen L, Liu M, Su N, Luo X, Yin L, Zhu Y, Feng JQ, Chen D, Qi H, Chen L, Xie Y. Zhang D, et al. Among authors: chen l, chen d, chen h. Nat Commun. 2021 Jul 19;12(1):4391. doi: 10.1038/s41467-021-24643-2. Nat Commun. 2021. PMID: 34282140 Free PMC article.

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