Hines RM - Search Results

1

Developmental seizures and mortality result from reducing GABA_A receptor α2-subunit interaction with collybistin.

Hines RM, Maric HM, Hines DJ, Modgil A, Panzanelli P, Nakamura Y, Nathanson AJ, Cross A, Deeb T, Brandon NJ, Davies P, Fritschy JM, Schindelin H, Moss SJ. Hines RM, et al. Nat Commun. 2018 Aug 7;9(1):3130. doi: 10.1038/s41467-018-05481-1. Nat Commun. 2018. PMID: 30087324 Free PMC article.

2

Human ARHGEF9 intellectual disability syndrome is phenocopied by a mutation that disrupts collybistin binding to the GABA_A receptor α2 subunit.

Hines DJ, Contreras A, Garcia B, Barker JS, Boren AJ, Moufawad El Achkar C, Moss SJ, Hines RM. Hines DJ, et al. Among authors: hines rm. Mol Psychiatry. 2022 Mar;27(3):1729-1741. doi: 10.1038/s41380-022-01468-z. Epub 2022 Feb 15. Mol Psychiatry. 2022. PMID: 35169261 Free PMC article.

3

Identification of a Core Amino Acid Motif within the α Subunit of GABA_ARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures.

Nathanson AJ, Zhang Y, Smalley JL, Ollerhead TA, Rodriguez Santos MA, Andrews PM, Wobst HJ, Moore YE, Brandon NJ, Hines RM, Davies PA, Moss SJ. Nathanson AJ, et al. Among authors: hines rm. Cell Rep. 2019 Jul 16;28(3):670-681.e8. doi: 10.1016/j.celrep.2019.06.014. Cell Rep. 2019. PMID: 31315046 Free PMC article.

4

[No title available]

[No authors listed] [No authors listed] PMID: 35546200

5

Disrupting the clustering of GABAA receptor α2 subunits in the frontal cortex leads to reduced γ-power and cognitive deficits.

Hines RM, Hines DJ, Houston CM, Mukherjee J, Haydon PG, Tretter V, Smart TG, Moss SJ. Hines RM, et al. Among authors: hines dj. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16628-33. doi: 10.1073/pnas.1308706110. Epub 2013 Sep 16. Proc Natl Acad Sci U S A. 2013. PMID: 24043839 Free PMC article.

6

The ability of BDNF to modify neurogenesis and depressive-like behaviors is dependent upon phosphorylation of tyrosine residues 365/367 in the GABA(A)-receptor γ2 subunit.

Vithlani M, Hines RM, Zhong P, Terunuma M, Hines DJ, Revilla-Sanchez R, Jurd R, Haydon P, Rios M, Brandon N, Yan Z, Moss SJ. Vithlani M, et al. Among authors: hines rm, hines dj. J Neurosci. 2013 Sep 25;33(39):15567-77. doi: 10.1523/JNEUROSCI.1845-13.2013. J Neurosci. 2013. PMID: 24068823 Free PMC article.

7

KCC2 activity is critical in limiting the onset and severity of status epilepticus.

Silayeva L, Deeb TZ, Hines RM, Kelley MR, Munoz MB, Lee HH, Brandon NJ, Dunlop J, Maguire J, Davies PA, Moss SJ. Silayeva L, et al. Among authors: hines rm. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3523-8. doi: 10.1073/pnas.1415126112. Epub 2015 Mar 2. Proc Natl Acad Sci U S A. 2015. PMID: 25733865 Free PMC article.

8

Functional regulation of GABAA receptors in nervous system pathologies.

Hines RM, Davies PA, Moss SJ, Maguire J. Hines RM, et al. Curr Opin Neurobiol. 2012 Jun;22(3):552-8. doi: 10.1016/j.conb.2011.10.007. Epub 2011 Oct 28. Curr Opin Neurobiol. 2012. PMID: 22036769 Free PMC article. Review.

9

Molecular Specialization of GABAergic Synapses on the Soma and Axon in Cortical and Hippocampal Circuit Function and Dysfunction.

Contreras A, Hines DJ, Hines RM. Contreras A, et al. Among authors: hines rm. Front Mol Neurosci. 2019 Jun 26;12:154. doi: 10.3389/fnmol.2019.00154. eCollection 2019. Front Mol Neurosci. 2019. PMID: 31297048 Free PMC article.

10

Behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-HT_2A receptor activation.

Contreras A, Khumnark M, Hines RM, Hines DJ. Contreras A, et al. Among authors: hines rm. Sci Rep. 2021 Jan 21;11(1):1925. doi: 10.1038/s41598-021-81552-6. Sci Rep. 2021. PMID: 33479368 Free PMC article.

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