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Novel single-chain antibody-targeted microbubbles for molecular ultrasound imaging of thrombosis: validation of a unique noninvasive method for rapid and sensitive detection of thrombi and monitoring of success or failure of thrombolysis in mice.
Wang X, Hagemeyer CE, Hohmann JD, Leitner E, Armstrong PC, Jia F, Olschewski M, Needles A, Peter K, Ahrens I. Wang X, et al. Circulation. 2012 Jun 26;125(25):3117-26. doi: 10.1161/CIRCULATIONAHA.111.030312. Epub 2012 May 30. Circulation. 2012. PMID: 22647975
Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated platelets.
Wang X, Palasubramaniam J, Gkanatsas Y, Hohmann JD, Westein E, Kanojia R, Alt K, Huang D, Jia F, Ahrens I, Medcalf RL, Peter K, Hagemeyer CE. Wang X, et al. Circ Res. 2014 Mar 28;114(7):1083-93. doi: 10.1161/CIRCRESAHA.114.302514. Epub 2014 Feb 9. Circ Res. 2014. PMID: 24508759
Dual-contrast molecular imaging allows noninvasive characterization of myocardial ischemia/reperfusion injury after coronary vessel occlusion in mice by magnetic resonance imaging.
von Elverfeldt D, Maier A, Duerschmied D, Braig M, Witsch T, Wang X, Mauler M, Neudorfer I, Menza M, Idzko M, Zirlik A, Heidt T, Bronsert P, Bode C, Peter K, von Zur Muhlen C. von Elverfeldt D, et al. Among authors: wang x. Circulation. 2014 Aug 19;130(8):676-87. doi: 10.1161/CIRCULATIONAHA.113.008157. Epub 2014 Jun 20. Circulation. 2014. PMID: 24951772
Single-chain antibody conjugated to a cage amine chelator and labeled with positron-emitting copper-64 for diagnostic imaging of activated platelets.
Alt K, Paterson BM, Ardipradja K, Schieber C, Buncic G, Lim B, Poniger SS, Jakoby B, Wang X, O'Keefe GJ, Tochon-Danguy HJ, Scott AM, Ackermann U, Peter K, Donnelly PS, Hagemeyer CE. Alt K, et al. Among authors: wang x. Mol Pharm. 2014 Aug 4;11(8):2855-63. doi: 10.1021/mp500209a. Epub 2014 Jul 14. Mol Pharm. 2014. PMID: 24999533
A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry.
Alt K, Paterson BM, Westein E, Rudd SE, Poniger SS, Jagdale S, Ardipradja K, Connell TU, Krippner GY, Nair AK, Wang X, Tochon-Danguy HJ, Donnelly PS, Peter K, Hagemeyer CE. Alt K, et al. Among authors: wang x. Angew Chem Int Ed Engl. 2015 Jun 22;54(26):7515-9. doi: 10.1002/anie.201411507. Epub 2015 May 11. Angew Chem Int Ed Engl. 2015. PMID: 25962581
209,124 results
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