Ryan MD - Search Results

1

"Therapeutic applications of the 'NPGP' family of viral 2As".

Luke GA, Ryan MD. Luke GA, et al. Among authors: ryan md. Rev Med Virol. 2018 Nov;28(6):e2001. doi: 10.1002/rmv.2001. Epub 2018 Aug 9. Rev Med Virol. 2018. PMID: 30094875 Review.

2

Occurrence, function and evolutionary origins of '2A-like' sequences in virus genomes.

Luke GA, de Felipe P, Lukashev A, Kallioinen SE, Bruno EA, Ryan MD. Luke GA, et al. Among authors: ryan md. J Gen Virol. 2008 Apr;89(Pt 4):1036-1042. doi: 10.1099/vir.0.83428-0. J Gen Virol. 2008. PMID: 18343847 Free PMC article.

3

Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal 'skip'.

Donnelly MLL, Luke G, Mehrotra A, Li X, Hughes LE, Gani D, Ryan MD. Donnelly MLL, et al. Among authors: ryan md. J Gen Virol. 2001 May;82(Pt 5):1013-1025. doi: 10.1099/0022-1317-82-5-1013. J Gen Virol. 2001. PMID: 11297676

4

The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences.

Donnelly MLL, Hughes LE, Luke G, Mendoza H, Ten Dam E, Gani D, Ryan MD. Donnelly MLL, et al. Among authors: ryan md. J Gen Virol. 2001 May;82(Pt 5):1027-1041. doi: 10.1099/0022-1317-82-5-1027. J Gen Virol. 2001. PMID: 11297677

5

E unum pluribus: multiple proteins from a self-processing polyprotein.

de Felipe P, Luke GA, Hughes LE, Gani D, Halpin C, Ryan MD. de Felipe P, et al. Among authors: ryan md. Trends Biotechnol. 2006 Feb;24(2):68-75. doi: 10.1016/j.tibtech.2005.12.006. Epub 2005 Dec 27. Trends Biotechnol. 2006. PMID: 16380176 Review.

6

Inhibition of 2A-mediated 'cleavage' of certain artificial polyproteins bearing N-terminal signal sequences.

de Felipe P, Luke GA, Brown JD, Ryan MD. de Felipe P, et al. Among authors: ryan md. Biotechnol J. 2010 Feb;5(2):213-23. doi: 10.1002/biot.200900134. Biotechnol J. 2010. PMID: 19946875 Free PMC article.

7

Self-processing polyproteins: a strategy for co-expression of multiple proteins in plants.

Luke GA, De Felipe P, Cowton VM, Hughes LE, Halpin C, Ryan MD. Luke GA, et al. Among authors: ryan md. Biotechnol Genet Eng Rev. 2006;23:239-52. doi: 10.1080/02648725.2006.10648086. Biotechnol Genet Eng Rev. 2006. PMID: 22530510 Review. No abstract available.

8

APE-type non-LTR retrotransposons of multicellular organisms encode virus-like 2A oligopeptide sequences, which mediate translational recoding during protein synthesis.

Odon V, Luke GA, Roulston C, de Felipe P, Ruan L, Escuin-Ordinas H, Brown JD, Ryan MD, Sukhodub A. Odon V, et al. Among authors: ryan md. Mol Biol Evol. 2013 Aug;30(8):1955-65. doi: 10.1093/molbev/mst102. Epub 2013 May 31. Mol Biol Evol. 2013. PMID: 23728794 Free PMC article.

9

'2A-Like' Signal Sequences Mediating Translational Recoding: A Novel Form of Dual Protein Targeting.

Roulston C, Luke GA, de Felipe P, Ruan L, Cope J, Nicholson J, Sukhodub A, Tilsner J, Ryan MD. Roulston C, et al. Among authors: ryan md. Traffic. 2016 Aug;17(8):923-39. doi: 10.1111/tra.12411. Epub 2016 Jun 2. Traffic. 2016. PMID: 27161495 Free PMC article.

10

Using the 2A Protein Coexpression System: Multicistronic 2A Vectors Expressing Gene(s) of Interest and Reporter Proteins.

Luke GA, Ryan MD. Luke GA, et al. Among authors: ryan md. Methods Mol Biol. 2018;1755:31-48. doi: 10.1007/978-1-4939-7724-6_3. Methods Mol Biol. 2018. PMID: 29671261

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